Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | HTT | P42858 | 3/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.70 |
| ▸ | GSK3A | P49840 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18954588 | 0.87 | ALDH1A1 (0.53) | ALDH1A1MAPTHTTHSD17B10GSK3A | |
| SCHEMBL18954789 | 0.85 | ALDH1A1 (0.71) | ALDH1A1MAPTHTTHSD17B10LMNA | |
| SCHEMBL18954534 | 0.85 | ALDH1A1 (0.50) | ALDH1A1MAPTHTTHSD17B10USP2 | |
| SCHEMBL27703276 | 0.79 | ALDH1A1 (0.76) | ALDH1A1MAPTHTTHSD17B10GSK3A | |
| SCHEMBL18954553 | 0.77 | MAPT (0.45) | ALDH1A1MAPTHTTHSD17B10TSHR | |
| SCHEMBL18954460 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MAPTHTTHSD17B10GSK3A | |
| SCHEMBL9179332 | 0.76 | ALDH1A1 (0.62) | ALDH1A1MAPTHTTHSD17B10GSK3A | |
| SCHEMBL18954621 | 0.75 | ALDH1A1 (0.40) | ALDH1A1MAPTHTTHSD17B10USP2 | |
| SCHEMBL18954646 | 0.75 | ALDH1A1 (0.45) | ALDH1A1MAPTHTTHSD17B10TSHR | |
| SCHEMBL18955736 | 0.74 | ALDH1A1 (0.74) | ALDH1A1MAPTHTTHSD17B10GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017099695-A1 | N-[(AMINOSULFONYL)PHENYL]-2-(1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)-HYDRAZINECARBOTHIOAMIDE DERIVATIVES FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS | ISTANBUL UNIVERSITESI REKTORLUGU (TR) | 2017-06-15 | — | — | WO | disclosed |