Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 20/20 | 0.56 |
| ▸ | GNA15 | P30679 | 1/20 | 0.49 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.49 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.49 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.49 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22474718 | 0.92 | FFAR1 (0.65) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL18963605 | 0.89 | FFAR1 (0.72) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL29423944 | 0.89 | FFAR1 (0.72) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL18940307 | 0.89 | FFAR1 (0.72) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL29423948 | 0.89 | FFAR1 (0.72) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL23952777 | 0.89 | FFAR1 (0.72) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL16845939 | 0.89 | FFAR1 (0.72) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL29423906 | 0.88 | FFAR1 (0.62) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL16845938 | 0.88 | FFAR1 (0.62) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL18959411 | 0.87 | FFAR1 (0.42) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834563-B2 | Antidiabetic substituted heteroaryl compounds | MERCK SHARP & DOHME CORP. (US) | 2017-12-05 | — | — | US | disclosed |
| US-20170166578-A1 | ANTIDIABETIC SUBSTITUTED HETEROARYL COMPOUNDS | MERCK SHARP & DOHME LLC | 2017-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170166578-A1 | ANTIDIABETIC SUBSTITUTED HETEROARYL COMPOUNDS | GPR119, GPR65, GPR55 | FFAR1 13/4885GNA15 564/4885SLC10A1 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.