Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10226406 | 0.91 | RXRA (0.54) | RXRARXRBMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6394555 | 0.91 | ALDH1A1 (0.46) | HIF1ASMN1; SMN2ALDH1A1CHRNB2CHRNB4 | |
| SCHEMBL21388410 | 0.88 | MAPT (0.43) | RXRARXRBMAPTHIF1ASMN1; SMN2 | |
| SCHEMBL16022462 | 0.83 | RXRA (0.47) | RXRARXRBMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7619064 | 0.81 | HIF1A (0.40) | MAPTHIF1ASMN1; SMN2ALDH1A1FFAR1 | |
| SCHEMBL439247 | 0.81 | SMN1; SMN2 (0.43) | MAPTHIF1ASMN1; SMN2ALDH1A1FFAR1 | |
| SCHEMBL13242652 | 0.81 | APP (0.54) | SMN1; SMN2ALDH1A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6388039 | 0.81 | APP (0.54) | SMN1; SMN2ALDH1A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL15915 | 0.81 | ALDH1A1 (0.58) | MAPTSMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL7628720 | 0.80 | SMN1; SMN2 (0.42) | MAPTHIF1ASMN1; SMN2ALDH1A1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170170400-A1 | COMPOSITIONS COMPRISING OXYGEN SUBSTITUTED BENZOCYCLOBUTENES AND DIENOPHILES, AND ELECTRONIC DEVICES CONTAINING THE SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-06-15 | — | — | US | disclosed |
| US-20170170400-A1 | COMPOSITIONS COMPRISING OXYGEN SUBSTITUTED BENZOCYCLOBUTENES AND DIENOPHILES, AND ELECTRONIC DEVICES CONTAINING THE SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-06-15 | — | — | US | disclosed |