SCHEMBL18960929

SCHEMBL18960929

c1ccc2c(c1)Oc1cccc(-c3cc(-c4cccc5c4sc4ccccc45)nc(-c4ccc5c6ccccc6c6ccccc6c5c4)n3)c1O2

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.41
PRKDC P78527 7/20 0.35
PIK3CD O00329 2/20 0.32
PIK3CB P42338 2/20 0.32
PARP14 Q460N5 1/20 0.32
MAPT P10636 1/20 0.31
BRD4 O60885 1/20 0.31
PIK3CA P42336 1/20 0.31
MTOR P42345 1/20 0.31
PIK3CG P48736 1/20 0.31
KCNH2 Q12809 1/20 0.31
BRDT Q58F21 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18960955 0.90 ALOX5 (0.42) ALOX5PRKDCPIK3CDPIK3CBPARP14
SCHEMBL18960960 0.89 ALOX5 (0.32) ALOX5MAPT
SCHEMBL18960927 0.84 ALOX5 (0.38) ALOX5PRKDCPIK3CDPIK3CBPARP14
SCHEMBL18960951 0.84 ALOX5 (0.33) ALOX5MAPT
SCHEMBL18960958 0.83 MEN1 (0.40) MAPT
SCHEMBL18961071 0.82 ALOX5 (0.47) ALOX5PRKDCPIK3CDPIK3CBPARP14
SCHEMBL25049898 0.82 ALOX5 (0.46) ALOX5PRKDCPIK3CDPIK3CBPARP14
SCHEMBL18960932 0.82 MEN1 (0.40) MAPT
SCHEMBL25050205 0.81 ALOX5 (0.45) ALOX5PRKDCPIK3CDPIK3CBPARP14
SCHEMBL18960942 0.79 CHEK2 (0.35) ALOX5MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170170405-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-15 US disclosed
US-20170170405-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-15 US disclosed