Sugi Predict

Sugi Predict / Compounds / SCHEMBL18960951

SCHEMBL18960951

SCHEMBL18960951

c1ccc2c(c1)Oc1cccc(-c3nc(-c4ccc5sc6ccccc6c5c4)nc(-c4ccc5c6ccccc6c6ccccc6c5c4)n3)c1O2

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 1/20 0.33
▸ GPR3 P46089 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ RAB9A P51151 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ CYP1A2 P05177 1/20 0.30
▸ AHR P35869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18960955 0.91 ALOX5 (0.42) ALOX5MAPT
SCHEMBL18960960 0.90 ALOX5 (0.32) ALOX5ALDH1A1MAPTHPGD
SCHEMBL18961054 0.85 ALOX5 (0.35) ALOX5GPR3ALDH1A1MAPTHPGD
SCHEMBL18960935 0.84 ALDH1A1 (0.36) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL18960929 0.84 ALOX5 (0.41) ALOX5MAPT
SCHEMBL18960953 0.83 ALOX5 (0.31) ALOX5
SCHEMBL18960937 0.82 CHEK2 (0.36) ALOX5ALDH1A1MAPTHPGDRAB9A
SCHEMBL18960966 0.81 AHR (0.34) AHR
SCHEMBL18960954 0.79 ALOX5 (0.43) ALOX5ALDH1A1MAPTHPGDRAB9A
SCHEMBL25586401 0.78 ALOX5 (0.34) ALOX5GPR3ALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170170405-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-15 — — US disclosed
US-20170170405-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-15 — — US disclosed