SCHEMBL18960960

SCHEMBL18960960

c1ccc2c(c1)Oc1cccc(-c3cc(-c4ccc5sc6ccccc6c5c4)nc(-c4ccc5c6ccccc6c6ccccc6c5c4)n3)c1O2

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.32
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18960951 0.90 ALOX5 (0.33) ALOX5ALDH1A1MAPTHPGD
SCHEMBL18960929 0.89 ALOX5 (0.41) ALOX5MAPT
SCHEMBL18960958 0.85 MEN1 (0.40) KDM4EMEN1ALDH1A1LMNAMAPT
SCHEMBL18960932 0.84 MEN1 (0.40) KDM4EMEN1ALDH1A1LMNAMAPT
SCHEMBL18960933 0.84
SCHEMBL18960942 0.84 CHEK2 (0.35) ALOX5KDM4EMEN1ALDH1A1LMNA
SCHEMBL18961054 0.82 ALOX5 (0.35) ALOX5ALDH1A1MAPTHPGD
SCHEMBL18960955 0.82 ALOX5 (0.42) ALOX5MAPT
SCHEMBL18960975 0.79 MEN1 (0.45) KDM4EMEN1ALDH1A1LMNAMAPT
SCHEMBL15501811 0.79 GPR3 (0.48) ALOX5KDM4EMEN1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170170405-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-15 US disclosed
US-20170170405-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-15 US disclosed