SCHEMBL1896116

SCHEMBL1896116

COC(=O)C(C)=CC(C)N

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
GABRP O00591 2/20 0.33
GABRD O14764 2/20 0.33
GABRA1 P14867 2/20 0.33
GABRB1 P18505 2/20 0.33
GABRG2 P18507 2/20 0.33
GABRB3 P28472 2/20 0.33
GABRA5 P31644 2/20 0.33
GABRA3 P34903 2/20 0.33
GABRA2 P47869 2/20 0.33
GABRB2 P47870 2/20 0.33
GABRA4 P48169 2/20 0.33
GABRE P78334 2/20 0.33
GABRA6 Q16445 2/20 0.33
GABRG1 Q8N1C3 2/20 0.33
GABRG3 Q99928 2/20 0.33
GABRQ Q9UN88 2/20 0.33
TSHR P16473 1/20 0.33
MAP3K7 O43318 1/20 0.32
TAB1 Q15750 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28313743 0.82 TSHR (0.44) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL9654192 0.81 ALDH1A1 (0.40) ALDH1A1TSHRMAP3K7TAB1
SCHEMBL666919 0.81 ALDH1A1 (0.40) ALDH1A1TSHRMAP3K7TAB1
SCHEMBL3200879 0.79 ALDH1A1 (0.39) ALDH1A1TSHRMAP3K7TAB1
SCHEMBL3200874 0.79 ALDH1A1 (0.39) ALDH1A1TSHRMAP3K7TAB1
SCHEMBL27542945 0.79 ALDH1A1 (0.39) ALDH1A1TSHRMAP3K7TAB1
SCHEMBL3292256 0.77 ALDH1A1 (0.33) ALDH1A1MAP3K7TAB1
SCHEMBL940837 0.77 GABRP (0.30) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL3289816 0.77 GLO1 (0.44) ALDH1A1TSHRMAPTHPGD
SCHEMBL12391156 0.76 ALDH1A1 (0.36) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023136797-A2 A BILAYER TABLET COMPOSITION COMPRISING AMORPHOUS DAPAGLIFLOZIN AND METFORMIN SANOVEL ILAC SANAYI VE TICARET ANONIM SIRKETI (TR) 2023-07-20 WO claimed
EP-4212150-A1 A BILAYER TABLET COMPOSITION COMPRISING AMORPHOUS DAPAGLIFLOZIN AND METFORMIN SANOVEL ILAC SANAYI VE TICARET A.S. (TR) 2023-07-19 EP claimed
US-10611871-B2 Star polymers and compositions thereof THE LUBRIZOL CORPORATION (US) 2020-04-07 US claimed
US-20160008469-A9 METHOD FOR PREPARING BIOMEDICAL METAL ALLOY MATERIAL WITH MULTI-DRUG DELIVERY SYSTEM Kwungpook National University Industry Academic Cooperation Foundation (KR) 2016-01-14 US claimed
US-20150202168-A1 ORAL FILM FORMULATIONS COMPRISING DAPOXETINE AND TADALAFIL Sanovel llac Sanayi Ve Ticaret Anonim Sirketi (TR) 2015-07-23 US claimed
EP-2698147-B1 Oral Film Formulations Comprising Dapoxetine and Tadalafil SANOVEL ILAC SANAYI VE TICARET AS (TR) 2015-07-22 EP claimed
WO-2014027980-A1 ORAL FILM FORMULATIONS COMPRISING DAPOXETINE AND TADALAFIL SANOVEL ILAC SANAYI VE TICARET ANONIM SIRKETI (TR) 2014-02-20 WO claimed
EP-2698147-A1 Oral Film Formulations Comprising Dapoxetine and Tadalafil Sanovel Ilac Sanayi ve Ticaret A.S. (TR) 2014-02-19 EP claimed
US-20130164346-A1 METHOD FOR PREPARING BIOMEDICAL METAL ALLOY MATERIAL WITH MULTI-DRUG DELIVERY SYSTEM Kwungpook National University Industry Academic Cooperation Foundation (KR) 2013-06-27 US claimed
EP-1791420-A1 INDICATOR GRANULAR MATERIAL Mars, Incorporated (US) 2007-06-06 EP claimed
WO-2006032353-A1 INDICATOR GRANULAR MATERIAL MARS INCORPORATED (US) 2006-03-30 WO claimed
CN-118028547-A Suede finishing agent for leather, finishing process and leather 辛集市梅花皮业有限公司 2024-05-14 CN disclosed
EP-3411339-B1 PROCESS FOR AEROBIC NITRITATION OF AMMONIA MICROVI BIOTECH INC (US) 2023-11-29 EP disclosed
WO-2023136797-A2 A BILAYER TABLET COMPOSITION COMPRISING AMORPHOUS DAPAGLIFLOZIN AND METFORMIN SANOVEL ILAC SANAYI VE TICARET ANONIM SIRKETI (TR) 2023-07-20 WO disclosed
EP-4212150-A1 A BILAYER TABLET COMPOSITION COMPRISING AMORPHOUS DAPAGLIFLOZIN AND METFORMIN SANOVEL ILAC SANAYI VE TICARET A.S. (TR) 2023-07-19 EP disclosed
US-4085020-A Electrodeposition of aqueous dispersions of copolymers of polyethylenically unsaturated epoxy-amine adducts DESOTO, INC. (US) 1978-04-18 US disclosed
US-4085161-A Electrodeposition of aqueous dispersions of copolymers of polyethylenically unsaturated epoxy adducts including blocked isocyanate monomer DESOTO, INC. (US) 1978-04-18 US disclosed
US-4036800-A Electrodeposition of aqueous dispersions of amine functional urethane copolymers DESOTO, INC. (US) 1977-07-19 US disclosed
US-4033917-A Electrodeposition of aqueous dispersions of copolymers of polyethylenically unsaturated epoxy-amine adducts DESOTO, INC. (US) 1977-07-05 US disclosed
US-3976615-A ELECTRODEPOSITION, COATINGS DESOTO, INC. (US) 1976-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150202168-A1 ORAL FILM FORMULATIONS COMPRISING DAPOXETINE AND TADALAFIL PDE5A, PDE3A, PDE3B ALDH1A1 1504/4885GABRP 2305/4885GABRD 2777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.