SCHEMBL18962011

SCHEMBL18962011

c1ccc(-c2nc(-n3c4ccccc4c4ccc5c6ccccc6sc5c43)nc3c2sc2ccccc23)cc1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNKS O95271 3/20 0.32
TNKS2 Q9H2K2 3/20 0.32
HRH4 Q9H3N8 1/20 0.32
MAPT P10636 4/20 0.31
NPSR1 Q6W5P4 3/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
LMNA P02545 1/20 0.31
MAPK1 P28482 1/20 0.31
RECQL P46063 1/20 0.31
MMP14 P50281 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
LIMK1 P53667 1/20 0.31
CDK5 Q00535 1/20 0.31
CDK5R1 Q15078 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18961906 0.98 TNKS (0.33) TNKSTNKS2HRH4MAPTNPSR1
SCHEMBL18962082 0.94 LIMK1 (0.32) TNKSTNKS2MAPTLIMK1
SCHEMBL18962121 0.93 LIMK1 (0.33) TNKSTNKS2MAPTLIMK1PIM1
SCHEMBL26743738 0.92 CYP1A1 (0.33) MAPTNPSR1MEN1KMT2ALMNA
SCHEMBL18165428 0.90 L3MBTL1 (0.37) TNKSTNKS2HRH4MAPTNPSR1
SCHEMBL17251081 0.90 EGLN1 (0.32) LIMK1CDK5CDK5R1
SCHEMBL16905780 0.89 TNKS (0.36) TNKSTNKS2HRH4MAPTNPSR1
SCHEMBL18961908 0.89 TNKS (0.32) TNKSTNKS2MAPT
SCHEMBL26743410 0.89
SCHEMBL19679643 0.88 L3MBTL1 (0.32) TNKSTNKS2HRH4MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588110-B2 Heterocyclic compound and organic light emitting device comprising the same LT MATERIALS CO., LTD. (KR) 2023-02-21 US disclosed
US-11367839-B2 Compound for organic electric element, organic electric element using the same, and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2022-06-21 US disclosed
US-10873034-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-12-22 US disclosed
US-20200373499-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LT MATERIALS CO., LTD. (KR) 2020-11-26 US disclosed
US-10011608-B2 Compound for organic electronic element, organic electronic element using the same, and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2018-07-03 US disclosed
US-10011608-B2 Compound for organic electronic element, organic electronic element using the same, and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2018-07-03 US disclosed
US-20170237015-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-08-17 US disclosed
US-20170237015-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-08-17 US disclosed
US-20170166581-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2017-06-15 US disclosed
US-20170166581-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2017-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170237015-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CCNA1, ARL1 TNKS 1917/4885TNKS2 1690/4885HRH4 1955/4885
US-10011608-B2 Compound for organic electronic element, organic electronic element using the same, and an electronic device thereof PIEZO1, OR51E2, OCIAD1 TNKS 4042/4885TNKS2 4072/4885HRH4 4752/4885
US-11588110-B2 Heterocyclic compound and organic light emitting device comprising the same CRY1, CYP1A1, CYP1B1 TNKS 3028/4885TNKS2 3575/4885HRH4 1813/4885
US-11367839-B2 Compound for organic electric element, organic electric element using the same, and an electronic device thereof ORAI2, KCNJ2, OR10J3 TNKS 2912/4885TNKS2 1996/4885HRH4 4619/4885
US-10873034-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CCNA1, ARL1 TNKS 1917/4885TNKS2 1690/4885HRH4 1955/4885
US-20170166581-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF PIEZO1, OR51E2, OCIAD1 TNKS 4042/4885TNKS2 4072/4885HRH4 4752/4885
US-20200373499-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CRY1, CYP1A1, CYP1B1 TNKS 3028/4885TNKS2 3575/4885HRH4 1813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.