SCHEMBL1896346

SCHEMBL1896346

O=C1c2ccccc2-c2ccc(Br)c(Br)c21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.54
MEN1 O00255 7/20 0.54
KMT2A Q03164 7/20 0.54
PTPRC P08575 5/20 0.54
MAOA P21397 5/20 0.54
NPC1 O15118 5/20 0.54
HTT P42858 4/20 0.54
POLB P06746 4/20 0.54
LMNA P02545 4/20 0.54
S100A4 P26447 4/20 0.54
SMN1; SMN2 Q16637 4/20 0.54
RAB9A P51151 4/20 0.54
APAF1 O14727 3/20 0.54
GALK1 P51570 3/20 0.54
BLM P54132 3/20 0.54
NPSR1 Q6W5P4 3/20 0.54
TDP2 O95551 2/20 0.54
PLA2G1B P04054 2/20 0.54
PLCG1 P19174 2/20 0.54
PPARG P37231 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30570825 0.98 PTPRC (0.56) MAPTMEN1KMT2APTPRCMAOA
SCHEMBL2679985 0.98 PTPRC (0.56) MAPTMEN1KMT2APTPRCMAOA
SCHEMBL357951 0.92 MAPT (0.53) MAPTMEN1KMT2APTPRCMAOA
SCHEMBL7773334 0.91 PABPC1 (0.47) MAPTMEN1KMT2APTPRCMAOA
SCHEMBL8956246 0.85 BCL2 (0.51) MAPTMEN1KMT2APTPRCMAOA
SCHEMBL11781324 0.82 PTPRC (0.40) MAPTMEN1KMT2APTPRCMAOA
SCHEMBL16491894 0.80 MAPT (0.61) MAPTMEN1KMT2APTPRCMAOA
SCHEMBL28863786 0.80 PTPRC (0.46) MAPTMEN1KMT2APTPRCMAOA
SCHEMBL28808731 0.80 ALDH1A1 (0.53) MAPTMEN1KMT2APTPRCMAOA
SCHEMBL6905740 0.80 MEN1 (0.76) MAPTMEN1KMT2APTPRCMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110092890-B Organic conjugated nano poly lattice and preparation method and application thereof 南京邮电大学 2022-09-30 CN claimed
CN-114516790-A Synthesis and luminescence of bis-benzophenanthracenone pentanone discotic liquid crystal compound 四川师范大学 2022-05-20 CN disclosed
US-20220002552-A1 SUBSTITUTED POLYFLUORENE COMPOUNDS BioLegend, Inc. (US) 2022-01-06 US disclosed
US-11155714-B2 Substituted polyfluorene compounds BioLegend, Inc. (US) 2021-10-26 US disclosed
WO-2020226126-A1 COMPOUND HAVING FLUORENE SKELETON AND METHOD FOR PRODUCING SAME 帝人株式会社 2020-11-12 WO disclosed
WO-2020085222-A1 CRYSTAL OF COMPOUND HAVING FLUORENE SKELETON AND METHOD FOR PRODUCING SAME 帝人株式会社 2020-04-30 WO disclosed
US-20190203052-A1 SUBSTITUTED POLYFLUORENE COMPOUNDS BIOLEGEND (US) 2019-07-04 US disclosed
EP-3085692-B1 NOVEL 3,6-DISUBSTITUTED FLUORENE DERIVATIVES NISSAN CHEMICAL CORP (JP) 2018-11-21 EP disclosed
US-10000694-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2018-06-19 US disclosed
WO-2018009861-A1 SUBSTITUTED POLYFLUORENE COMPOUNDS BIOLEGEND (US) 2018-01-11 WO disclosed
EP-1284258-B1 Mono-, oligo- and polyalkylidenefluorenes and their use as charge transport materials MERCK PATENT GMBH (DE) 2006-02-08 EP disclosed
WO-2005049548-A1 CROSSLINKABLE SUBSTITUTED FLUORENE COMPOUNDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-06-02 WO disclosed
US-6805922-B2 Crosslinked liquid crystalline polymer MERCK PATENT GMBH (DE) 2004-10-19 US disclosed
EP-1427768-A2 CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF Covion Organic Semiconductors GmbH (DE) 2004-06-16 EP disclosed
US-20030067267-A1 Mono-, oligo-and polyalkylidenefluorenes and their use as charge transport materials MERCK PATENT GMBH (DE) 2003-04-10 US disclosed
WO-2003020790-A2 CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2003-03-13 WO disclosed
EP-1284258-A2 Mono-, oligo- and polyalkylidenefluorenes and their use as charge transport materials MERCK PATENT GmbH (DE) 2003-02-19 EP disclosed
EP-1053578-B1 USE OF SPIRO COMPOUNDS AS LASER DYES COVION ORGANIC SEMICONDUCTORS (DE) 2002-05-08 EP disclosed
EP-1053578-A1 USE OF SPIRO COMPOUNDS AS LASER DYES Axiva GmbH (DE) 2000-11-22 EP disclosed
WO-1999040655-A1 USE OF SPIRO COMPOUNDS AS LASER DYES AXIVA GMBH (DE) 1999-08-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10000694-B2 Materials for organic electroluminescent devices OR10J3, EPCAM, L1CAM MAPT 550/4885MEN1 1226/4885KMT2A 1418/4885
US-11155714-B2 Substituted polyfluorene compounds PARG, PFAS, PARN MAPT 1970/4885MEN1 1028/4885KMT2A 3560/4885
US-20220002552-A1 SUBSTITUTED POLYFLUORENE COMPOUNDS PARG, PFAS, PARN MAPT 1970/4885MEN1 1028/4885KMT2A 3560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.