Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.52 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 14/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 14/20 | 0.43 |
| ▸ | ERBB3 | P21860 | 14/20 | 0.43 |
| ▸ | ERBB4 | Q15303 | 14/20 | 0.43 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.41 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4544706 | 0.75 | EGFR (0.60) | DYRK1AEGFRERBB2ERBB3ERBB4 | |
| SCHEMBL13186164 | 0.74 | DYRK1A (0.59) | DYRK1AIRAK4BRAFTNNI3KEGFR | |
| SCHEMBL14747699 | 0.73 | DYRK1A (0.53) | DYRK1AIRAK4BRAFTNNI3KEGFR | |
| SCHEMBL4544688 | 0.73 | TTBK1 (0.64) | EGFRERBB2ERBB3ERBB4PDPK1 | |
| SCHEMBL15500305 | 0.72 | KDR (0.42) | DYRK1AIRAK4CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL15224219 | 0.72 | DYRK1A (0.47) | DYRK1AIRAK4BRAFTNNI3KEGFR | |
| SCHEMBL4544686 | 0.72 | LMNA (0.61) | EGFRCYP1A2CYP2D6TSHR | |
| SCHEMBL28346037 | 0.71 | TTBK1 (0.59) | PDPK1 | |
| SCHEMBL12709725 | 0.71 | TTBK1 (0.59) | PDPK1 | |
| SCHEMBL18194341 | 0.70 | XDH (0.51) | DYRK1AIRAK4TNNI3KYTHDC1YTHDF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170166571-A1 | TREATMENT OF H. PYLORI INFECTIONS USING MTAN INHIBITORS | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) | 2017-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170166571-A1 | TREATMENT OF H. PYLORI INFECTIONS USING MTAN INHIBITORS | MTAP, PNP, UNG | DYRK1A 4468/4885IRAK4 4081/4885BRAF 3976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.