Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 19/20 | 0.50 |
| ▸ | GLS | O94925 | 1/20 | 0.42 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1896409 | 0.93 | GLS (0.42) | ANO1GLS | |
| SCHEMBL1950210 | 0.91 | ANO1 (0.55) | ANO1GLSANO2 | |
| SCHEMBL1954085 | 0.85 | ANO1 (0.53) | ANO1GLSANO2 | |
| SCHEMBL12271719 | 0.84 | ANO1 (0.57) | ANO1ANO2 | |
| SCHEMBL1954895 | 0.83 | ANO1 (0.54) | ANO1ANO2 | |
| SCHEMBL1898226 | 0.76 | CASP3 (0.44) | ANO1 | |
| SCHEMBL12756756 | 0.76 | GLS (0.49) | ANO1GLS | |
| SCHEMBL12271221 | 0.75 | MEN1 (0.56) | ANO1GLS | |
| SCHEMBL1954030 | 0.73 | ANO1 (0.63) | ANO1ANO2 | |
| SCHEMBL1907629 | 0.73 | ABL1 (0.56) | ANO1ANO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321303-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | Calcimedica, Inc. (US) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010027875-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2010-03-11 | — | — | WO | disclosed |