Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1954085 | 0.84 | ANO1 (0.53) | CASP3SENP8SENP7SENP6ANO1 | |
| SCHEMBL1954914 | 0.82 | CASP3 (0.62) | CASP3SENP8SENP7SENP6ANO1 | |
| SCHEMBL1950495 | 0.81 | MEN1 (0.49) | CASP3SENP8SENP7SENP6ANO1 | |
| SCHEMBL1950210 | 0.80 | ANO1 (0.55) | ANO1 | |
| SCHEMBL12271221 | 0.77 | MEN1 (0.56) | CASP3SENP8SENP7SENP6ANO1 | |
| SCHEMBL1896408 | 0.76 | ANO1 (0.50) | ANO1 | |
| SCHEMBL12271719 | 0.75 | ANO1 (0.57) | ANO1MEN1KMT2A | |
| SCHEMBL1952393 | 0.72 | ADORA2A (0.49) | CASP3SENP8SENP7SENP6ANO1 | |
| SCHEMBL1896409 | 0.71 | GLS (0.42) | CASP3SENP8SENP7SENP6ANO1 | |
| SCHEMBL1954473 | 0.71 | MEN1 (0.55) | CASP3SENP8SENP7SENP6ANO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321303-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | Calcimedica, Inc. (US) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010027875-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2010-03-11 | — | — | WO | disclosed |