Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30874370 | 0.76 | KDM4E (0.47) | KDM4EALDH1A1PIN1PIN4NPSR1 | |
| SCHEMBL18956056 | 0.76 | KDM4E (0.47) | KDM4EALDH1A1PIN1PIN4NPSR1 | |
| SCHEMBL18956134 | 0.76 | KDM4E (0.45) | KDM4EALDH1A1PIN1PIN4NPSR1 | |
| SCHEMBL2824950 | 0.74 | ALDH1A1 (0.50) | KDM4EALDH1A1PIN1PIN4NPSR1 | |
| SCHEMBL25073871 | 0.74 | KDM4E (0.43) | KDM4EALDH1A1PIN1PIN4NPSR1 | |
| SCHEMBL30279192 | 0.74 | KDM4E (0.43) | KDM4EALDH1A1PIN1PIN4NPSR1 | |
| SCHEMBL30279183 | 0.71 | MITF (0.42) | KDM4EALDH1A1PIN1PIN4MAPT | |
| SCHEMBL5855748 | 0.70 | KMT2A (0.48) | KDM4EALDH1A1PIN1PIN4LMNA | |
| Hydrochloric Acid SCHEMBL27199364 | 0.69 | ALDH1A1 (0.43) | KDM4EALDH1A1PIN1PIN4MAPT | |
| SCHEMBL13837758 | 0.69 | GSK3A (0.45) | KDM4EALDH1A1PIN1PIN4RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386591-B1 | HETEROAROMATIC NMDA RECEPTOR MODULATORS AND USES THEREOF | CADENT THERAPEUTICS INC (US) | 2020-06-24 | — | — | EP | disclosed |
| WO-2017100591-A1 | HETEROAROMATIC NMDA RECEPTOR MODULATORS AND USES THEREOF | LUC THERAPEUTICS (US) | 2017-06-15 | — | — | WO | disclosed |