Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 7/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30279192 | 1.00 | KDM4E (0.43) | KDM4EALDH1A1TNFPIN1PIN4 | |
| SCHEMBL30874370 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1TNFPIN1PIN4 | |
| SCHEMBL18956056 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1TNFPIN1PIN4 | |
| SCHEMBL30279202 | 0.82 | KMT2A (0.42) | KDM4EALDH1A1POLBNPC1 | |
| SCHEMBL25073869 | 0.82 | KMT2A (0.42) | KDM4EALDH1A1POLBNPC1 | |
| SCHEMBL20037274 | 0.76 | ALDH1A1 (0.50) | KDM4EALDH1A1TNFGAAL3MBTL1 | |
| SCHEMBL18956134 | 0.75 | KDM4E (0.45) | KDM4EALDH1A1PIN1PIN4POLB | |
| SCHEMBL18955878 | 0.75 | PSMB1 (0.58) | KDM4EALDH1A1TNF | |
| SCHEMBL20786879 | 0.75 | TNF (0.51) | KDM4EALDH1A1TNFPOLB | |
| SCHEMBL20512455 | 0.75 | ALDH1A1 (0.42) | KDM4EALDH1A1TNFNPSR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023021278-A1 | PHENYL- AND PYRIDOPYRAZOLE DERIVATIVES AS INHIBITORS OF DDR1 | REDX PHARMA PLC (GB) | 2023-02-23 | — | — | WO | disclosed |