Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.63 |
| ▸ | MAOB | P27338 | 2/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | DDX3X | O00571 | 2/20 | 0.43 |
| ▸ | MIF | P14174 | 2/20 | 0.43 |
| ▸ | CD74 | P04233 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16491147 | 0.83 | MAOA (0.73) | MAOAMAOBCA2CA9L3MBTL1 | |
| SCHEMBL29828549 | 0.78 | MAOA (0.66) | MAOAMAOBDDX3XMIF | |
| SCHEMBL29828653 | 0.77 | P2RX7 (0.67) | MAOAMAOBGLACA2CA9 | |
| SCHEMBL22532624 | 0.75 | MAOA (0.61) | MAOAMAOBGLACA2CA9 | |
| SCHEMBL20046238 | 0.74 | MAOA (0.68) | MAOAMAOBCA2CA9L3MBTL1 | |
| SCHEMBL10447579 | 0.73 | NOTUM (0.54) | MAOAGLAL3MBTL1PTGS2NOTUM | |
| SCHEMBL29980293 | 0.73 | MAOA (0.57) | MAOAMAOBCA2CA9L3MBTL1 | |
| SCHEMBL28935748 | 0.72 | MAOA (0.60) | MAOAMAOBCA2CA9L3MBTL1 | |
| SCHEMBL22873389 | 0.72 | MAOA (0.64) | MAOAMAOBCA2CA9L3MBTL1 | |
| Terephthalic Acid SCHEMBL27799191 | 0.71 | MAPT (0.67) | CA2CA9CA5ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017100461-A1 | POLYNUCLEOTIDE CONSTRUCTS HAVING AN AUXILIARY MOIETY NON-BIOREVERSIBLY LINKED TO AN INTERNUCLEOSIDE PHOSPHATE OR PHOSPHOROTHIOATE | SOLSTICE BIOLOGICS, LTD. (IE) | 2017-06-15 | — | — | WO | disclosed |