Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 9/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18965952 | 0.90 | CYP3A4 (0.53) | CYP3A4NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL18965856 | 0.86 | CYP3A4 (0.49) | CYP3A4NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL18965768 | 0.85 | CYP3A4 (0.52) | CYP3A4NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL17488172 | 0.83 | CYP3A4 (0.54) | CYP3A4NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL18965794 | 0.83 | CYP3A4 (0.49) | CYP3A4NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL18965974 | 0.83 | CYP3A4 (0.51) | CYP3A4NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL18960414 | 0.83 | CYP3A4 (0.54) | CYP3A4NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL17488173 | 0.82 | CYP3A4 (0.48) | CYP3A4NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL17488311 | 0.82 | CYP3A4 (0.48) | CYP3A4NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL18965817 | 0.82 | CYP3A4 (0.48) | CYP3A4NPC1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170166563-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2017-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170166563-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | ALOX5, ALOX15, ALOX12 | CYP3A4 261/4885NPC1 2764/4885RAB9A 3982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.