Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1898675 | 1.00 | ALDH1A1 (0.43) | ALDH1A1LMNASLC15A2MAPTTSHR | |
| SCHEMBL4245440 | 0.83 | KDM2A (0.43) | LMNASLC15A2MAPTTSHRMAPK1 | |
| SCHEMBL10936262 | 0.82 | LMNA (0.52) | ALDH1A1LMNAMAPTTSHRMAPK1 | |
| Isopropyl Alcohol SCHEMBL811815 | 0.80 | LMNA (0.50) | ALDH1A1LMNASLC15A2MAPTTSHR | |
| SCHEMBL16580864 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNASLC15A2MAPTTSHR | |
| SCHEMBL811107 | 0.79 | LMNA (0.54) | ALDH1A1LMNASLC15A2MAPTTSHR | |
| Propylene Glycol SCHEMBL602325 | 0.79 | LMNA (0.46) | ALDH1A1LMNASLC15A2MAPTTSHR | |
| SCHEMBL4567081 | 0.78 | ALDH1A1 (0.43) | ALDH1A1LMNASLC15A2MAPTTSHR | |
| SCHEMBL11816713 | 0.77 | LMNA (0.52) | ALDH1A1LMNASLC15A2MAPTTSHR | |
| SCHEMBL31573806 | 0.77 | TDP1 (0.38) | ALDH1A1LMNAMAPTTSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130052204-A1 | (POLY)-GLYCEROLPHOSPHATE-BASED ANTI-GRAM POSITIVE BACTERIAL VACCINE | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. | 2013-02-28 | — | — | US | disclosed |
| EP-2501403-A2 | (POLY)-GLYCEROLPHOSPHATE-BASED ANTI-GRAM POSITIVE BACTERIAL VACCINE | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (US) | 2012-09-26 | — | — | EP | disclosed |
| WO-2011060379-A2 | (POLY)-GLYCEROLPHOSPHATE-BASED ANTI-GRAM POSITIVE BACTERIAL VACCINE | SNAPPER CLIFFORD M (US) | 2011-05-19 | — | — | WO | disclosed |