Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19228009 | 0.90 | DRD2 (0.33) | DRD2HTR2ADRD3 | |
| SCHEMBL23837376 | 0.88 | SMYD3 (0.34) | MAPT | |
| SCHEMBL22667381 | 0.87 | MTNR1A (0.41) | NAMPTDRD2HTR2ADRD3MAPT | |
| SCHEMBL23130007 | 0.86 | AAK1 (0.32) | MAPT | |
| SCHEMBL19228024 | 0.85 | — | — | |
| SCHEMBL19228053 | 0.85 | L3MBTL1 (0.32) | — | |
| SCHEMBL18966461 | 0.85 | NAMPT (0.37) | NAMPTDRD2HTR2ADRD3MAPT | |
| SCHEMBL19663642 | 0.84 | MAPT (0.34) | MAPT | |
| SCHEMBL17337169 | 0.84 | NAMPT (0.38) | NAMPTDRD2HTR2ADRD3MAPT | |
| SCHEMBL17337165 | 0.84 | NAMPT (0.38) | NAMPTDRD2HTR2ADRD3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9637504-B2 | Beta-lactamase inhibitors | VenatoRx Pharmaceuticals, Inc. (US) | 2017-05-02 | — | — | US | disclosed |