Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.62 |
| ▸ | MAOA | P21397 | 5/20 | 0.62 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | KRAS | P01116 | 2/20 | 0.53 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.51 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10046634 | 0.87 | MAOB (0.63) | MAOBMAOABCHECYP1B1KRAS | |
| SCHEMBL25194702 | 0.87 | MAOB (0.63) | MAOBMAOABCHECYP1B1KRAS | |
| SCHEMBL7196575 | 0.82 | MAOB (0.72) | MAOBMAOABCHECYP1B1KRAS | |
| SCHEMBL7194771 | 0.82 | MAOB (0.72) | MAOBMAOABCHECYP1B1KRAS | |
| SCHEMBL7194766 | 0.82 | MAOB (0.72) | MAOBMAOABCHECYP1B1KRAS | |
| SCHEMBL7196578 | 0.82 | MAOB (0.72) | MAOBMAOABCHECYP1B1KRAS | |
| SCHEMBL3033674 | 0.82 | MAPT (0.64) | MAPT | |
| SCHEMBL6733854 | 0.79 | MAOB (0.85) | MAOBMAOABCHECYP1B1KRAS | |
| SCHEMBL6733848 | 0.79 | MAOB (0.85) | MAOBMAOABCHECYP1B1KRAS | |
| SCHEMBL9151812 | 0.77 | MAOB (0.62) | MAOBMAOABCHECYP1B1KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170168073-A1 | CHALCONE-UREA DERIVATIVES AS INSULIN SENSORS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170168073-A1 | CHALCONE-UREA DERIVATIVES AS INSULIN SENSORS | IAPP, INSR, GPR119 | MAOB 3635/4885MAOA 4107/4885BCHE 1056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.