SCHEMBL18969723

SCHEMBL18969723

CO[C@H]1[C@H](O)[C@H](O)[C@H](O[C@H]2[C@H](O)[C@H](O)[C@H](C)O[C@H]2C(=O)O)O[C@@H]1C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 6/20 0.39
▸ CXCL10 P02778 1/20 0.37
▸ CXCL8 P10145 1/20 0.37
▸ CCL2 P13500 1/20 0.37
▸ CCL5 P13501 1/20 0.37
▸ CXCL12 P48061 1/20 0.37
▸ FGF1 P05230 2/20 0.35
▸ AMY1A P0DUB6 1/20 0.34
▸ BDNF P23560 3/20 0.33
▸ PTN P21246 2/20 0.33
▸ MDK P21741 2/20 0.33
▸ SERPINC1 P01008 2/20 0.33
▸ M6PR P20645 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ ALOX15 P16050 1/20 0.32
▸ STAT3 P40763 1/20 0.32
▸ AMY2A P04746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29379116 1.00 F10 (0.39) F10CXCL10CXCL8CCL2CCL5
SCHEMBL19488918 1.00 F10 (0.39) F10CXCL10CXCL8CCL2CCL5
SCHEMBL12458629 0.89 F10 (0.43) F10CXCL10CXCL8CCL2CCL5
SCHEMBL22139521 0.89 F10 (0.43) F10CXCL10CXCL8CCL2CCL5
SCHEMBL12384884 0.89 F10 (0.43) F10CXCL10CXCL8CCL2CCL5
SCHEMBL12878540 0.89 F10 (0.43) F10CXCL10CXCL8CCL2CCL5
SCHEMBL12755226 0.89 F10 (0.43) F10CXCL10CXCL8CCL2CCL5
SCHEMBL20370858 0.89 F10 (0.43) F10CXCL10CXCL8CCL2CCL5
SCHEMBL20363547 0.89 F10 (0.43) F10CXCL10CXCL8CCL2CCL5
SCHEMBL20363815 0.89 F10 (0.43) F10CXCL10CXCL8CCL2CCL5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170165201-A1 PH-RESPONSIVE MUCOADHESIVE POLYMERIC ENCAPSULATED MICROORGANISMS MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2017-06-15 — — US disclosed
US-20170165201-A1 PH-RESPONSIVE MUCOADHESIVE POLYMERIC ENCAPSULATED MICROORGANISMS MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2017-06-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170165201-A1 PH-RESPONSIVE MUCOADHESIVE POLYMERIC ENCAPSULATED MICROORGANISMS HRH2, MUC1, TLR6 F10 1862/4885CXCL10 1015/4885CXCL8 1435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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