Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22730594 | 1.00 | SLC6A9 (0.34) | SLC6A9HSD17B10KDM4EALDH1A1USP2 | |
| SCHEMBL18970127 | 0.94 | TDP1 (0.34) | SLC6A9HSD17B10KDM4EALDH1A1USP2 | |
| SCHEMBL22730606 | 0.94 | TDP1 (0.34) | SLC6A9HSD17B10KDM4EALDH1A1USP2 | |
| SCHEMBL18970114 | 0.94 | TDP1 (0.34) | SLC6A9HSD17B10KDM4EALDH1A1USP2 | |
| SCHEMBL18970104 | 0.93 | HSD17B10 (0.38) | SLC6A9HSD17B10KDM4EALDH1A1USP2 | |
| SCHEMBL18970241 | 0.87 | SLC6A9 (0.36) | SLC6A9HSD17B10KDM4EALDH1A1KMT2A | |
| SCHEMBL18970111 | 0.87 | TDP1 (0.39) | SLC6A9HSD17B10KDM4EALDH1A1ALOX15 | |
| SCHEMBL18975209 | 0.83 | MAPT (0.31) | SLC6A9KDM4EALDH1A1USP2ALOX15 | |
| SCHEMBL22808775 | 0.82 | KMT2A (0.32) | KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL22730569 | 0.82 | MAPT (0.30) | SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3753929-A1 | DIMERIC CONTRAST AGENTS | Bracco Imaging SPA (IT) | 2020-12-23 | — | — | EP | disclosed |
| EP-3386954-B1 | DIMERIC CONTRAST AGENTS | BRACCO IMAGING SPA (IT) | 2020-12-02 | — | — | EP | disclosed |
| WO-2017098044-A1 | DIMERIC CONTRAST AGENTS | BRACCO IMAGING SPA (IT) | 2017-06-15 | — | — | WO | disclosed |