Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | EYA2 | O00167 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22730606 | 1.00 | TDP1 (0.34) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL18970114 | 1.00 | TDP1 (0.34) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL22730594 | 0.94 | SLC6A9 (0.34) | TDP1KDM4EALOX15PIK3CDSLC6A9 | |
| SCHEMBL18970106 | 0.94 | SLC6A9 (0.34) | TDP1KDM4EALOX15PIK3CDSLC6A9 | |
| SCHEMBL18970111 | 0.93 | TDP1 (0.39) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL18970104 | 0.87 | HSD17B10 (0.38) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL22808775 | 0.87 | KMT2A (0.32) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL22730603 | 0.85 | KDM4E (0.38) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL18970241 | 0.84 | SLC6A9 (0.36) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL20280987 | 0.81 | KDM4E (0.34) | KDM4EALOX15BLMPMP22HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3753929-A1 | DIMERIC CONTRAST AGENTS | Bracco Imaging SPA (IT) | 2020-12-23 | — | — | EP | disclosed |
| EP-3386954-B1 | DIMERIC CONTRAST AGENTS | BRACCO IMAGING SPA (IT) | 2020-12-02 | — | — | EP | disclosed |
| WO-2017098044-A1 | DIMERIC CONTRAST AGENTS | BRACCO IMAGING SPA (IT) | 2017-06-15 | — | — | WO | disclosed |