Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | EYA2 | O00167 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18970104 | 0.94 | HSD17B10 (0.38) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL18970114 | 0.93 | TDP1 (0.34) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL22730606 | 0.93 | TDP1 (0.34) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL18970127 | 0.93 | TDP1 (0.34) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL22730603 | 0.92 | KDM4E (0.38) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL18970241 | 0.91 | SLC6A9 (0.36) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL22730594 | 0.87 | SLC6A9 (0.34) | TDP1KDM4EALOX15SLC6A9HSD17B10 | |
| SCHEMBL18970106 | 0.87 | SLC6A9 (0.34) | TDP1KDM4EALOX15SLC6A9HSD17B10 | |
| SCHEMBL18975211 | 0.85 | BACE1 (0.48) | KDM4EHSD17B10KMT2AMEN1ALDH1A1 | |
| SCHEMBL18975189 | 0.81 | ALDH1A1 (0.44) | KDM4ELMNAADRA2ATSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210024500-A1 | DIMERIC CONTRAST AGENTS | BRACCO IMAGING S.P.A. (IT) | 2021-01-28 | — | — | US | disclosed |
| US-10882849-B2 | Dimeric contrast agents | BRACCO IMAGING S.P.A. (IT) | 2021-01-05 | — | — | US | disclosed |
| US-20200331893-A9 | DIMERIC CONTRAST AGENTS | BRACCO IMAGING S.P.A. (IT) | 2020-10-22 | — | — | US | disclosed |
| US-20190345142-A1 | DIMERIC CONTRAST AGENTS | BRACCO IMAGING S.P.A. (IT) | 2019-11-14 | — | — | US | disclosed |
| US-10407412-B2 | Dimeric contrast agents | BRACCO IMAGING S.P.A. (IT) | 2019-09-10 | — | — | US | disclosed |
| WO-2017098044-A1 | DIMERIC CONTRAST AGENTS | BRACCO IMAGING SPA (IT) | 2017-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200331893-A9 | DIMERIC CONTRAST AGENTS | CALCOCO2, NOD2, SLC39A14 | TDP1 4213/4885EYA2 4303/4885APP 4395/4885 |
| US-10882849-B2 | Dimeric contrast agents | CALCOCO2, NOD2, SLC39A14 | TDP1 4213/4885EYA2 4303/4885APP 4395/4885 |
| US-20210024500-A1 | DIMERIC CONTRAST AGENTS | CALCOCO2, NOD2, SLC39A14 | TDP1 4213/4885EYA2 4303/4885APP 4395/4885 |
| US-20190345142-A1 | DIMERIC CONTRAST AGENTS | CALCOCO2, NOD2, SLC39A14 | TDP1 4213/4885EYA2 4303/4885APP 4395/4885 |
| US-10407412-B2 | Dimeric contrast agents | CALCOCO2, NOD2, SLC39A14 | TDP1 4213/4885EYA2 4303/4885APP 4395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.