Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | HTR2B | P41595 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CLCN2 | P51788 | 2/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | KIF5B | P33176 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9230265 | 0.80 | TUBB1 (0.38) | HTR2AKMT2AALDH1A1HTR2CHTR2B | |
| SCHEMBL28196491 | 0.79 | RAPGEF4 (0.32) | HTR2AHTR2CHTR2BKCNH2 | |
| SCHEMBL14784158 | 0.79 | SMN1; SMN2 (0.48) | MEN1KMT2AALDH1A1SMN1; SMN2GLA | |
| SCHEMBL7939404 | 0.77 | HTR2A (0.47) | HTR2AMEN1KMT2AALDH1A1HTR2C | |
| SCHEMBL625995 | 0.77 | IDO1 (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2GLA | |
| SCHEMBL19756643 | 0.75 | HTR2A (0.46) | HTR2AMEN1KMT2AALDH1A1HTR2C | |
| SCHEMBL24724645 | 0.74 | MEP1B (0.44) | HTR2AMEN1KMT2AALDH1A1HTR2C | |
| SCHEMBL12957891 | 0.74 | HTR2A (0.41) | HTR2AMEN1KMT2AALDH1A1HTR2C | |
| SCHEMBL23723768 | 0.72 | ALDH1A1 (0.41) | HTR2AMEN1KMT2AALDH1A1HTR2C | |
| SCHEMBL23962788 | 0.72 | HTR2A (0.39) | HTR2AKMT2AALDH1A1HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2755944-B1 | BIARYLDERIVATIVES,THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI SA (FR) | 2017-06-14 | — | — | EP | disclosed |