Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ELANE | P08246 | 3/20 | 0.55 |
| ▸ | CTSG | P08311 | 2/20 | 0.55 |
| ▸ | STAT3 | P40763 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | RECQL | P46063 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13239412 | 0.88 | MAOA (0.76) | MAOAMAPTALDH1A1MAPK1TDP1 | |
| SCHEMBL23724036 | 0.86 | MAPT (0.77) | MAOAMAPTALDH1A1MAPK1TDP1 | |
| SCHEMBL30241843 | 0.86 | MAPT (0.77) | MAOAMAPTALDH1A1MAPK1TDP1 | |
| SCHEMBL30003218 | 0.82 | MAOA (0.72) | MAOAMAPTALDH1A1MAPK1TDP1 | |
| SCHEMBL5793791 | 0.82 | MAOA (0.72) | MAOAMAPTALDH1A1MAPK1TDP1 | |
| SCHEMBL9577702 | 0.79 | EGFR (0.62) | MAOAMAPTALDH1A1MAPK1TDP1 | |
| Droserone SCHEMBL30003199 | 0.79 | MAOA (0.67) | MAOAMAPTALDH1A1MAPK1TDP1 | |
| Droserone SCHEMBL5858407 | 0.79 | MAOA (0.67) | MAOAMAPTALDH1A1MAPK1TDP1 | |
| SCHEMBL2265203 | 0.78 | CA1 (0.47) | MAOAALDH1A1MAPK1TSHRSMN1; SMN2 | |
| SCHEMBL5174518 | 0.76 | MAOA (0.62) | MAOAMAPTALDH1A1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017099210-A1 | NAPHTHOQUINONE COMPOUND AND NUCLEAR FACTOR KAPPA-B (NF-κB) INHIBITOR COMPRISING SAME AS ACTIVE INGREDIENT | 株式会社ポーラファルマ | 2017-06-15 | — | — | WO | disclosed |