Droserone

Droserone

SCHEMBL30003199

CC1=C(O)C(=O)c2c(O)cccc2C1=O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 3/20 0.67
▸ MAPT P10636 6/20 0.64
▸ ALDH1A1 P00352 4/20 0.64
▸ TDP1 Q9NUW8 4/20 0.64
▸ MAPK1 P28482 3/20 0.64
▸ TSHR P16473 3/20 0.64
▸ HPGD P15428 3/20 0.64
▸ ALOX15 P16050 3/20 0.64
▸ SMN1; SMN2 Q16637 3/20 0.64
▸ HSD17B10 Q99714 3/20 0.64
▸ LMNA P02545 2/20 0.64
▸ MAOB P27338 2/20 0.64
▸ HTT P42858 1/20 0.64
▸ STAT3 P40763 4/20 0.59
▸ KMT2A Q03164 6/20 0.57
▸ KDM4E B2RXH2 5/20 0.57
▸ RECQL P46063 5/20 0.57
▸ MEN1 O00255 5/20 0.57
▸ ELANE P08246 3/20 0.57
▸ CYP3A4 P08684 3/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Droserone SCHEMBL5858407 1.00 MAOA (0.67) MAOAMAPTALDH1A1TDP1MAPK1
SCHEMBL5817676 0.92 MAOA (0.67) MAOAMAPTALDH1A1TDP1MAPK1
SCHEMBL30003218 0.88 MAOA (0.72) MAOAMAPTALDH1A1TDP1MAPK1
SCHEMBL5793791 0.88 MAOA (0.72) MAOAMAPTALDH1A1TDP1MAPK1
SCHEMBL27857026 0.85 MAOA (0.61) MAOAMAPTALDH1A1TDP1MAPK1
SCHEMBL5818633 0.84 MAOA (0.78) MAOAMAPTALDH1A1TDP1MAPK1
SCHEMBL23271809 0.81 NSD2 (0.43) MAOAMAPTALDH1A1TDP1MAPK1
SCHEMBL5174518 0.81 MAOA (0.62) MAOAMAPTALDH1A1TDP1MAPK1
SCHEMBL30003398 0.81 NSD2 (0.43) MAOAMAPTALDH1A1TDP1MAPK1
Anthrarufin SCHEMBL187843 0.81 MAOA (1.00) MAOAMAPTALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3843696-B1 PROCESS AND COMPOSITION FOR COLORING KERATIN FIBERS OREAL (FR) 2025-04-09 — — EP disclosed
WO-2024048429-A1 COSMETIC PROCESS USING PARTICLE WITH MICROPROTRUSION L'OREAL (FR) 2024-03-07 — — WO disclosed
WO-2023228870-A1 COMPOSITION FOR COLORING KERATIN FIBERS L'OREAL (FR) 2023-11-30 — — WO disclosed
US-11672743-B2 Composition for keratin fibers comprising a direct dye L'OREAL (FR) 2023-06-13 — — US disclosed
US-20230051189-A1 COSMETIC PROCESS USING MICRONEEDLE SHEET L'OREAL (FR) 2023-02-16 — — US disclosed
US-11540992-B2 Process and composition for coloring keratin fibers L'OREAL (FR) 2023-01-03 — — US disclosed
CN-110891980-B Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2022-09-30 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11540992-B2 Process and composition for coloring keratin fibers KRT18, PRKDC, KIF5C MAOA 1476/4885MAPT 1335/4885ALDH1A1 394/4885
US-11672743-B2 Composition for keratin fibers comprising a direct dye KRT18, MKI67, DSG1 MAOA 2518/4885MAPT 678/4885ALDH1A1 2227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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