Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18914373 | 0.89 | ADRA2A (0.36) | KDM4EHTR2AHTR2CSLC6A4SLC6A2 | |
| SCHEMBL18908172 | 0.89 | ADRA2A (0.36) | KDM4EHTR2AHTR2CSLC6A4SLC6A2 | |
| SCHEMBL18959750 | 0.88 | HTR2A (0.37) | KDM4EHTR2AHTR2CSLC6A4SLC6A2 | |
| SCHEMBL19361587 | 0.87 | HTR2A (0.36) | KDM4EHTR2AHTR2CSLC6A4SLC6A2 | |
| SCHEMBL18964398 | 0.86 | KDM4E (0.40) | KDM4EHTR2AHTR2CSLC6A4SLC6A2 | |
| SCHEMBL18909765 | 0.83 | CA1 (0.41) | SLC6A4 | |
| SCHEMBL18907014 | 0.82 | USP2 (0.41) | KDM4EHTR2AHTR2CSLC6A4SLC6A2 | |
| SCHEMBL18909751 | 0.82 | KDM4E (0.39) | KDM4EHTR2AHTR2CSLC6A4SLC6A2 | |
| SCHEMBL18908175 | 0.81 | KCNH2 (0.38) | KDM4EHTR2AHTR2CHTR1ADRD2 | |
| SCHEMBL18971798 | 0.80 | SMN1; SMN2 (0.39) | KDM4EHTR2AHTR2CSLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170166584-A1 | TRIAZOLE ACC INHIBITORS AND USES THEREOF | Nimbus Apollo, Inc. | 2017-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170166584-A1 | TRIAZOLE ACC INHIBITORS AND USES THEREOF | ACACA, ACACB, ACAT1 | KDM4E 2407/4885HTR2A 4785/4885HTR2C 4420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.