Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 16/20 | 0.51 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20833581 | 0.89 | MRGPRX4 (0.49) | MRGPRX4 | |
| SCHEMBL18973700 | 0.89 | BTN3A1 (0.48) | MRGPRX4BTN3A1ELANE | |
| SCHEMBL18973553 | 0.89 | BTN3A1 (0.48) | MRGPRX4BTN3A1ELANE | |
| SCHEMBL18973482 | 0.87 | BTN3A1 (0.49) | MRGPRX4BTN3A1ELANE | |
| SCHEMBL22081623 | 0.85 | BTN3A1 (0.46) | MRGPRX4BTN3A1 | |
| SCHEMBL22065158 | 0.85 | BTN3A1 (0.48) | BTN3A1ELANE | |
| SCHEMBL22065040 | 0.85 | BTN3A1 (0.48) | MRGPRX4BTN3A1ELANE | |
| SCHEMBL22066289 | 0.85 | BTN3A1 (0.52) | BTN3A1ELANE | |
| SCHEMBL22065782 | 0.83 | BTN3A1 (0.46) | MRGPRX4BTN3A1FFAR1ELANE | |
| SCHEMBL18973566 | 0.82 | ALDH1A1 (0.46) | BTN3A1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220402962-A1 | SYNTHESIS OF PHOSPHATE DERIVATIVES | NuCana plc (GB) | 2022-12-22 | — | — | US | disclosed |
| US-20210009625-A1 | DIASTEREOSELECTIVE SYNTHESIS OF PHOSPHATE DERIVATIVES | LAURUS LABS PRIVATE LTD (IN) | 2021-01-14 | — | — | US | disclosed |
| US-10774104-B2 | Diastereoselective synthesis of phosphate derivatives | LAURUS LABS PRIVATE LTD (IN) | 2020-09-15 | — | — | US | disclosed |
| US-20200181186-A1 | SYNTHESIS OF PHOSPHATE DERIVATIVES | NuCana plc (GB) | 2020-06-11 | — | — | US | disclosed |
| US-20200181190-A1 | SYNTHESIS OF 3'-DEOXYADENOSINE-5'-O-[PHENYL(BENZYLOXY-L-ALANINYL)]PHOSPHATE (NUC-7738) | NuCana plc (GB) | 2020-06-11 | — | — | US | disclosed |
| WO-2017098252-A1 | DIASTEREOSELECTIVE SYNTHESIS OF PHOSPHATE DERIVATIVES AND OF THE GEMCITABINE PRODRUG NUC-1031 | NUCANA BIOMED LIMITED (GB) | 2017-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10774104-B2 | Diastereoselective synthesis of phosphate derivatives | TYMP, PNP, DPYD | MRGPRX4 3782/4885BTN3A1 4678/4885FFAR1 3192/4885 |
| US-20200181186-A1 | SYNTHESIS OF PHOSPHATE DERIVATIVES | PPA1, PPIP5K2, TYMP | MRGPRX4 4643/4885BTN3A1 4531/4885FFAR1 4598/4885 |
| US-20220402962-A1 | SYNTHESIS OF PHOSPHATE DERIVATIVES | PNP, NTPCR, TYMP | MRGPRX4 4449/4885BTN3A1 2948/4885FFAR1 3028/4885 |
| US-20210009625-A1 | DIASTEREOSELECTIVE SYNTHESIS OF PHOSPHATE DERIVATIVES | TYMP, PNP, DPYD | MRGPRX4 4020/4885BTN3A1 4228/4885FFAR1 3570/4885 |
| US-20200181190-A1 | SYNTHESIS OF 3'-DEOXYADENOSINE-5'-O-[PHENYL(BENZYLOXY-L-ALANINYL)]PHOSPHATE (NUC-7738) | PNP, NT5C2, DUT | MRGPRX4 4099/4885BTN3A1 3995/4885FFAR1 3174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.