Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 4/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | ERN1 | O75460 | 2/20 | 0.53 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.53 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.50 |
| ▸ | DHFR | P00374 | 1/20 | 0.50 |
| ▸ | HNF4A | P41235 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | KMO | O15229 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4340852 | 0.92 | ERN1 (0.61) | ABCC1ABCB1CRHBPCRHR2ERN1 | |
| SCHEMBL1180549 | 0.91 | ERN1 (0.64) | ABCC1ABCB1CRHBPCRHR2ERN1 | |
| SCHEMBL29878741 | 0.91 | CRHBP (0.68) | ABCC1ABCB1CRHBPCRHR2KCNMA1 | |
| SCHEMBL3559913 | 0.91 | CRHBP (0.68) | ABCC1ABCB1CRHBPCRHR2KCNMA1 | |
| SCHEMBL28537073 | 0.89 | CRHBP (0.66) | ABCC1ABCB1CRHBPCRHR2KCNMA1 | |
| Benzoic Acid SCHEMBL28359564 | 0.86 | CASP6 (0.64) | LMNAALDH1A1TP53HPGDTSHR | |
| SCHEMBL9318576 | 0.84 | CRHBP (0.65) | ABCC1ABCB1CRHBPCRHR2KCNMA1 | |
| 2,4-Dinitrophenol SCHEMBL8898603 | 0.83 | TP53 (0.72) | MAPTKDM4EALDH1A1TP53HPGD | |
| Benzoic Acid SCHEMBL28772982 | 0.82 | CASP6 (0.53) | CRHBPCRHR2LMNAALDH1A1TP53 | |
| SCHEMBL8923085 | 0.82 | ALOX5 (0.51) | ABCC1ABCB1CRHBPCRHR2KCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8570481-B2 | Liquid crystal material, liquid crystal display device, liquid crystal optical space modulation device, and liquid crystal shutter | SONY CORPORATION (JP) | 2013-10-29 | — | — | US | disclosed |
| US-20110102731-A1 | LIQUID CRYSTAL MATERIAL, LIQUID CRYSTAL DISPLAY DEVICE, LIQUID CRYSTAL OPTICAL SPACE MODULATION DEVICE, AND LIQUID CRYSTAL SHUTTER | SONY CORPORATION (JP) | 2011-05-05 | — | — | US | disclosed |
| US-20100085531-A1 | LIQUID CRYSTAL MOLECULE, LIQUID CRYSTAL MATERIAL, LIQUID CRYSTAL DISPLAY DEVICE AND LIQUID CRYSTAL OPTICAL SPATIAL MODULATION DEVICE | SONY CORPORATION (JP) | 2010-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100085531-A1 | LIQUID CRYSTAL MOLECULE, LIQUID CRYSTAL MATERIAL, LIQUID CRYSTAL DISPLAY DEVICE AND LIQUID CRYSTAL OPTICAL SPATIAL MODULATION DEVICE | CXCR1, CCR3, CXCR2 | ABCC1 4433/4885ABCB1 4487/4885CRHBP 2069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.