Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | MC3R | P41968 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2554139 | 0.98 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2KMT2ADGAT1 | |
| SCHEMBL1461124 | 0.79 | KDM4E (0.47) | NPC1RAB9ASMN1; SMN2KMT2APOLB | |
| SCHEMBL14906735 | 0.78 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2KMT2APOLB | |
| SCHEMBL8887619 | 0.78 | BAZ2B (0.50) | NPC1RAB9ASMN1; SMN2KMT2APOLB | |
| SCHEMBL2558377 | 0.78 | POLB (0.61) | NPC1RAB9ASMN1; SMN2KMT2APOLB | |
| SCHEMBL30568667 | 0.78 | POLB (0.61) | NPC1RAB9ASMN1; SMN2KMT2APOLB | |
| SCHEMBL14906734 | 0.77 | RAB9A (0.47) | NPC1RAB9ASMN1; SMN2KMT2APOLB | |
| SCHEMBL504660 | 0.74 | ALDH1A1 (0.46) | NPC1RAB9ASMN1; SMN2KMT2ADGAT1 | |
| SCHEMBL23230633 | 0.74 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2KMT2APOLB | |
| Hydrochloric Acid SCHEMBL4430965 | 0.73 | KDM4E (0.44) | NPC1RAB9ASMN1; SMN2KMT2ADGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE46943-E1 | Radioprotector compounds and methods | PETER MACCALLUM CANCER INSTITUTE (AU) | 2018-07-10 | — | — | US | disclosed |
| EP-2556058-B1 | RADIOPROTECTOR COMPOUNDS AND METHODS | PETER MACCALLUM CANCER INST (AU) | 2017-06-14 | — | — | EP | disclosed |