Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26870955 | 0.93 | ALDH1A1 (0.49) | ALDH1A1TSHRTP53MEN1KMT2A | |
| SCHEMBL24394464 | 0.89 | TDP1 (0.54) | ALDH1A1TSHRTP53MEN1KMT2A | |
| SCHEMBL14969345 | 0.89 | TDP1 (0.54) | ALDH1A1TSHRTP53MEN1KMT2A | |
| SCHEMBL5598711 | 0.89 | TDP1 (0.54) | ALDH1A1TSHRTP53MEN1KMT2A | |
| SCHEMBL18230814 | 0.85 | PKM (0.57) | ALDH1A1TSHRTP53MEN1KMT2A | |
| SCHEMBL13385083 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TSHRTP53MEN1KMT2A | |
| SCHEMBL26870931 | 0.82 | TDP1 (0.59) | ALDH1A1TSHRTP53MEN1KMT2A | |
| SCHEMBL18230811 | 0.81 | HPGD (0.42) | ALDH1A1TSHRTP53MEN1KMT2A | |
| SCHEMBL18535693 | 0.81 | ALDH1A1 (0.55) | ALDH1A1TSHRTP53MEN1KMT2A | |
| SCHEMBL20727163 | 0.81 | ALDH1A1 (0.55) | ALDH1A1TSHRTP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521707-B1 | BISPHENOL DERIVATIVES AND THEIR USE AS ANDROGEN RECEPTOR ACTIVITY MODULATORS | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2017-06-14 | — | — | EP | disclosed |