SCHEMBL1897433

SCHEMBL1897433

CCCCCc1nnn([C@@H](C)O)n1

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.35
SPHK1 Q9NYA1 4/20 0.32
DAGLA Q9Y4D2 1/20 0.32
GPR84 Q9NQS5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4409333 0.86 MIF (0.33) MIFDAGLAGPR84
SCHEMBL4403680 0.84 CYP19A1 (0.34) MIF
SCHEMBL1899853 0.82 NPSR1 (0.39) SPHK1DAGLA
SCHEMBL4407194 0.80 DAGLA (0.31) DAGLA
SCHEMBL7507404 0.80 NPSR1 (0.38) DAGLA
SCHEMBL7501875 0.77 DAGLA (0.38) SPHK1DAGLA
SCHEMBL4411011 0.74 GPR84 (0.38) MIFGPR84
SCHEMBL7510274 0.74 MAPT (0.41) GPR84
SCHEMBL7506150 0.74 MAPT (0.41) GPR84
SCHEMBL7508587 0.74 MAPT (0.38) GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9434970-B2 Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester SK BIOPHARMACEUTICALS CO., LTD. (KR) 2016-09-06 US disclosed
US-9434970-B2 Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester SK BIOPHARMACEUTICALS CO., LTD. (KR) 2016-09-06 US disclosed
US-20150252398-A1 METHOD FOR PREPARATION OF CARBAMIC ACID (R)-1-ARYL-2-TETRAZOLYL-ETHYL ESTER SK BIOPHARMACEUTICALS CO LTD (KR) 2015-09-10 US disclosed
US-20150252398-A1 METHOD FOR PREPARATION OF CARBAMIC ACID (R)-1-ARYL-2-TETRAZOLYL-ETHYL ESTER SK BIOPHARMACEUTICALS CO LTD (KR) 2015-09-10 US disclosed
US-9068207-B2 Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester SK BIOPHARMACEUTICALS CO. LTD. (KR) 2015-06-30 US disclosed
US-9068207-B2 Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester SK BIOPHARMACEUTICALS CO. LTD. (KR) 2015-06-30 US disclosed
US-20140073018-A1 Method for Preparation of Carbamic Acid (R)-1-Aryl-2 Tetrazolyl-Ethyl Ester SK BIOPHARMACEUTICALS CO. LTD. (KR) 2014-03-13 US disclosed
US-20140073018-A1 Method for Preparation of Carbamic Acid (R)-1-Aryl-2 Tetrazolyl-Ethyl Ester SK BIOPHARMACEUTICALS CO. LTD. (KR) 2014-03-13 US disclosed
US-8404461-B2 Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester SK Biopharmaceutical Co. Ltd. (KR) 2013-03-26 US disclosed
US-8404461-B2 Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester SK Biopharmaceutical Co. Ltd. (KR) 2013-03-26 US disclosed
US-20110111467-A1 Method for Preparation of Carbamic Acid (R)-1-Aryl-2-Tetrazolyl-Ethyl Ester SK BIOPHARMACEUTICALS CO. LTD. (KR) 2011-05-12 US disclosed
US-20110111467-A1 Method for Preparation of Carbamic Acid (R)-1-Aryl-2-Tetrazolyl-Ethyl Ester SK BIOPHARMACEUTICALS CO. LTD. (KR) 2011-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110111467-A1 Method for Preparation of Carbamic Acid (R)-1-Aryl-2-Tetrazolyl-Ethyl Ester CES1, ADH1A, ADH1C MIF 4854/4885SPHK1 1678/4885DAGLA 204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.