Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.38 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.38 |
| ▸ | GLRB | P48167 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30067738 | 1.00 | KDM4E (0.44) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7815749 | 0.80 | AADAT (0.36) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL28537633 | 0.80 | MEN1 (0.45) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL17974970 | 0.75 | MEN1 (0.49) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL26017423 | 0.75 | BRD4 (0.49) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL29557464 | 0.75 | BRD4 (0.49) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL769455 | 0.75 | BRD4 (0.49) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL24664741 | 0.74 | ALDH1A1 (0.65) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9135785 | 0.74 | HDAC4 (0.47) | LMNAHDAC4HDAC7HDAC5EGFR | |
| SCHEMBL5321137 | 0.73 | AADAT (0.46) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017099695-A1 | N-[(AMINOSULFONYL)PHENYL]-2-(1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)-HYDRAZINECARBOTHIOAMIDE DERIVATIVES FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS | ISTANBUL UNIVERSITESI REKTORLUGU (TR) | 2017-06-15 | — | — | WO | disclosed |