SCHEMBL18975259

SCHEMBL18975259

O=CCC(=O)CC(=O)CCCCCCCCCCCCCO

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.43
FFAR1 O14842 1/20 0.43
FFAR4 Q5NUL3 1/20 0.43
FNTA P49354 1/20 0.38
FNTB P49356 1/20 0.38
KDM4E B2RXH2 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
GAA P10253 2/20 0.35
HAO1 Q9UJM8 1/20 0.34
CAMK2A Q9UQM7 1/20 0.31
HDAC3 O15379 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30
HDAC5 Q9UQL6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18975252 0.89 GPR84 (0.48) GPR84FFAR1FFAR4FNTAFNTB
SCHEMBL19817118 0.87 GPR84 (0.44) GPR84FFAR1FFAR4FNTAFNTB
SCHEMBL13160784 0.84 GPR84 (0.57) GPR84FFAR1FFAR4FNTAFNTB
SCHEMBL15621025 0.80
SCHEMBL25303773 0.80 GPR84 (0.52) GPR84FFAR1FFAR4FNTAFNTB
SCHEMBL26136419 0.78 HAO1 (0.50) GPR84FFAR1FFAR4HAO1
SCHEMBL28460206 0.77 HAO1 (0.44) HAO1
SCHEMBL28257446 0.76 ALDH1A1 (0.30)
SCHEMBL7266153 0.75 KDM4E (0.40) FNTAFNTBKDM4EHAO1
SCHEMBL12855872 0.74 GPR84 (0.46) GPR84FFAR1FFAR4FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170166679-A1 POLYURETHANE MATERIALS FORMED FROM UNSATURATED PLANT OILS VIA AN ALKYNE ZIPPER REACTION INTERNATIONAL BUSINESS MACHINES CORPORATION 2017-06-15 US disclosed