Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18975191 | 0.91 | ALDH1A1 (0.41) | ALDH1A1POLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL22562924 | 0.86 | ALDH1A1 (0.37) | ALDH1A1POLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL5557205 | 0.84 | ALDH1A1 (0.46) | ALDH1A1POLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL22446608 | 0.83 | ALDH1A1 (0.39) | ALDH1A1POLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL18975189 | 0.81 | ALDH1A1 (0.44) | ALDH1A1POLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL22446610 | 0.75 | POLB (0.42) | ALDH1A1POLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL18975269 | 0.74 | BACE1 (0.45) | ALDH1A1POLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL2570674 | 0.74 | LMNA (0.43) | ALDH1A1POLBL3MBTL1NPC1SMN1; SMN2 | |
| SCHEMBL18975218 | 0.74 | POLB (0.42) | ALDH1A1POLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL5551381 | 0.74 | ALDH1A1 (0.43) | ALDH1A1POLBMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017098038-A1 | CONTRAST AGENTS | BRACCO IMAGING SPA (IT) | 2017-06-15 | — | — | WO | disclosed |