Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22446608 | 0.92 | ALDH1A1 (0.39) | ALDH1A1POLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL18975286 | 0.91 | ALDH1A1 (0.41) | ALDH1A1POLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL5557205 | 0.83 | ALDH1A1 (0.46) | ALDH1A1POLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL22562924 | 0.80 | ALDH1A1 (0.37) | ALDH1A1POLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL18975189 | 0.80 | ALDH1A1 (0.44) | ALDH1A1POLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL22446610 | 0.74 | POLB (0.42) | ALDH1A1POLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL22446635 | 0.74 | ADRA1B (0.36) | ALDH1A1POLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL18975269 | 0.73 | BACE1 (0.45) | ALDH1A1POLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL5551381 | 0.73 | ALDH1A1 (0.43) | ALDH1A1POLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL18975218 | 0.73 | POLB (0.42) | ALDH1A1POLBMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11021451-B2 | Contrast agents | BRACCO IMAGING S.P.A. (IT) | 2021-06-01 | — | — | US | disclosed |
| EP-3386953-B1 | CONTRAST AGENTS | BRACCO IMAGING SPA (IT) | 2020-10-21 | — | — | EP | disclosed |
| US-20200325108-A1 | CONTRAST AGENTS | BRACCO IMAGING S.P.A. (IT) | 2020-10-15 | — | — | US | disclosed |
| US-10781188-B2 | Contrast agents | BRACCO IMAGING S.P.A. (IT) | 2020-09-22 | — | — | US | disclosed |
| WO-2017098038-A1 | CONTRAST AGENTS | BRACCO IMAGING SPA (IT) | 2017-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11021451-B2 | Contrast agents | SLC39A14, ABCB7, SLC40A1 | ALDH1A1 4417/4885POLB 3285/4885MEN1 323/4885 |
| US-20200325108-A1 | CONTRAST AGENTS | SLC39A14, ABCB7, SLC40A1 | ALDH1A1 4417/4885POLB 3285/4885MEN1 323/4885 |
| US-10781188-B2 | Contrast agents | SLC39A14, ABCB7, SLC40A1 | ALDH1A1 4417/4885POLB 3285/4885MEN1 323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.