Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | BMP1 | P13497 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PDE8B | O95263 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18977435 | 0.90 | ALDH1A1 (0.41) | RAB9AALDH1A1NPC1KDM4EHSD11B1 | |
| SCHEMBL18977432 | 0.80 | ALDH1A1 (0.36) | RAB9AALDH1A1NPC1KDM4EHSD11B1 | |
| SCHEMBL2655815 | 0.78 | OPRL1 (0.41) | TSHRRECQLHRH4RAB9AALDH1A1 | |
| SCHEMBL16364797 | 0.76 | OPRL1 (0.39) | TSHRRECQLHRH4RAB9AALDH1A1 | |
| SCHEMBL15479746 | 0.74 | BMP1 (0.40) | TSHRRECQLRAB9AALDH1A1OPRL1 | |
| SCHEMBL7176775 | 0.72 | HRH4 (0.59) | HRH4MEN1KMT2A | |
| SCHEMBL16364796 | 0.72 | KDM4E (0.38) | RAB9AALDH1A1OPRL1KDM4EHSD11B1 | |
| SCHEMBL15479751 | 0.71 | BMP1 (0.39) | TSHRRECQLRAB9AALDH1A1OPRL1 | |
| SCHEMBL29161733 | 0.71 | BMP1 (0.34) | TSHRRECQLHRH4RAB9AALDH1A1 | |
| SCHEMBL29161719 | 0.70 | SIGMAR1 (0.36) | TSHRRECQLHRH4RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2703392-B1 | 5-MEMBERED RING AROMATIC HETEROCYCLIC DERIVATIVE HAVING NPY Y5 RECEPTOR ANTAGONISTIC ACTIVITY | SHIONOGI & CO (JP) | 2017-06-14 | — | — | EP | disclosed |