Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.43 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14637585 | 0.88 | CTSK (0.55) | PAX8TDP1MMP1MMP3MMP9 | |
| SCHEMBL10135741 | 0.88 | CTSK (0.55) | PAX8TDP1MMP1MMP3MMP9 | |
| SCHEMBL969253 | 0.87 | PAX8 (0.53) | PAX8TDP1MMP1MMP3MMP9 | |
| SCHEMBL7922903 | 0.85 | PAX8 (0.51) | PAX8TDP1MMP1MMP3MMP9 | |
| SCHEMBL13043257 | 0.85 | CTSK (0.56) | PAX8TDP1MMP1MMP3MMP9 | |
| SCHEMBL18978665 | 0.82 | CTSK (0.53) | PAX8TDP1MMP1MMP3MMP9 | |
| SCHEMBL23680296 | 0.82 | PAX8 (0.49) | PAX8TDP1MMP1MMP3MMP9 | |
| SCHEMBL12947605 | 0.82 | PAX8 (0.49) | PAX8TDP1MMP1MMP3MMP9 | |
| SCHEMBL18791196 | 0.81 | KLK7 (0.50) | TDP1MMP1MMP3MMP9MAPT | |
| SCHEMBL10242762 | 0.80 | CTSK (0.49) | PAX8TDP1MAPTCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017098533-A2 | PROCESS FOR PREPARATION OF LISDEXAMPHETAMINE | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2017-06-15 | — | — | WO | disclosed |