Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 1.00 |
| ▸ | NPC1 | O15118 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1900773 | 0.83 | NPSR1 (0.90) | RAB9ANPC1KMT2ANPSR1MAPT | |
| SCHEMBL7744959 | 0.81 | NPSR1 (1.00) | RAB9ANPC1KMT2ANPSR1MAPT | |
| SCHEMBL1897745 | 0.81 | NPSR1 (0.71) | RAB9ANPC1KMT2ANPSR1MAPT | |
| SCHEMBL2079137 | 0.76 | MAPT (0.62) | RAB9ANPC1KMT2ANPSR1MAPT | |
| SCHEMBL144387 | 0.75 | NPSR1 (0.76) | RAB9ANPC1KMT2ANPSR1MAPT | |
| SCHEMBL147011 | 0.75 | NPSR1 (0.65) | RAB9ANPC1KMT2ANPSR1MAPT | |
| SCHEMBL1902360 | 0.73 | KMT2A (0.57) | RAB9ANPC1KMT2ANPSR1MAPT | |
| SCHEMBL15165519 | 0.73 | CYP1A2 (0.58) | RAB9ANPC1KMT2ANPSR1MAPT | |
| SCHEMBL10073088 | 0.71 | LMNA (0.66) | RAB9ANPC1KMT2ANPSR1MAPT | |
| SCHEMBL5178107 | 0.71 | GRN (0.67) | RAB9ANPC1KMT2ANPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252156-B1 | BLOCKADE OF VOLTAGE DEPENDENT SODIUM CHANNELS | UCL BUSINESS PLC (GB) | 2011-05-04 | — | — | EP | disclosed |