SCHEMBL1897917

SCHEMBL1897917

Fc1ccc(COc2c(Br)cccc2-c2cccc(C=Cc3ccccc3)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER1 P34995 2/20 0.39
ALDH1A1 P00352 4/20 0.37
KDM4E B2RXH2 4/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
MAPT P10636 3/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
MAOB P27338 4/20 0.36
MAOA P21397 2/20 0.36
KMT2A Q03164 5/20 0.36
NPSR1 Q6W5P4 3/20 0.36
MEN1 O00255 3/20 0.36
GRM4 Q14833 3/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
TSHR P16473 2/20 0.36
GRM5 P41594 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1899002 0.88 PTGER1 (0.39) PTGER1ALDH1A1KDM4ESMN1; SMN2MAPT
SCHEMBL1642995 0.77 KMT2A (0.42) PTGER1ALDH1A1KDM4ESMN1; SMN2MAPT
SCHEMBL1643444 0.77 PTGER1 (0.47) PTGER1ALDH1A1KDM4ESMN1; SMN2MAPT
SCHEMBL1902193 0.76 FEN1 (0.44) PTGER1ALDH1A1KDM4ESMN1; SMN2MAPT
SCHEMBL30834993 0.74 THRA (0.39) PTGER1MAPTL3MBTL1MAOBHPGD
SCHEMBL19830904 0.74 THRA (0.39) PTGER1MAPTL3MBTL1MAOBHPGD
SCHEMBL28284783 0.70 GRM5 (0.41) ALDH1A1KDM4ESMN1; SMN2MAPTL3MBTL1
SCHEMBL12766848 0.66 PTGER1 (0.47) PTGER1KDM4EL3MBTL1MAOBKMT2A
SCHEMBL1641975 0.66 PTGER1 (0.47) PTGER1KDM4EL3MBTL1MAOBKMT2A
SCHEMBL13429878 0.66 MAOB (0.50) MAPTMAOBMAOAKMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2493935-A2 CATALYST COMPOUNDS AND USE THEREOF Exxonmobil Chemical Patents Inc. (US) 2012-09-05 EP disclosed
WO-2011056431-A2 CATALYST COMPOUNDS AND USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-05-12 WO disclosed