Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1897917 | 0.88 | PTGER1 (0.39) | PTGER1ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL1902193 | 0.77 | FEN1 (0.44) | PTGER1ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL1641585 | 0.77 | PTGER1 (0.40) | PTGER1ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL1641975 | 0.75 | PTGER1 (0.47) | PTGER1KDM4EL3MBTL1MAOBKMT2A | |
| SCHEMBL8406052 | 0.71 | LCK (0.48) | PTGER1ALDH1A1KDM4EMAOBMAOA | |
| SCHEMBL8406054 | 0.71 | LCK (0.48) | PTGER1ALDH1A1KDM4EMAOBMAOA | |
| SCHEMBL1759276 | 0.67 | NPC1 (0.42) | PTGER1KDM4EMAPTKMT2ANPC1 | |
| SCHEMBL1894260 | 0.67 | CCNB2 (0.52) | PTGER1ALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL1758846 | 0.66 | KDM1A (0.45) | PTGER1ALDH1A1KDM4ESMN1; SMN2MAOB | |
| SCHEMBL12766736 | 0.66 | PTGER1 (0.40) | PTGER1ALDH1A1KDM4ESMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493935-A2 | CATALYST COMPOUNDS AND USE THEREOF | Exxonmobil Chemical Patents Inc. (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011056431-A2 | CATALYST COMPOUNDS AND USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-05-12 | — | — | WO | disclosed |