Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1899002 | 0.77 | PTGER1 (0.39) | GRM4KDM4EALDH1A1RAB9AHDAC6 | |
| SCHEMBL1643036 | 0.76 | FEN1 (0.47) | FEN1PKMALOX5APRXRARXRB | |
| SCHEMBL1897917 | 0.76 | PTGER1 (0.39) | GRM4KDM4EALDH1A1RAB9AHDAC6 | |
| SCHEMBL1643430 | 0.75 | FEN1 (0.43) | FEN1HPGDGRM5ALOX5APRXRA | |
| SCHEMBL1638838 | 0.71 | MAOA (0.51) | FEN1RAB9ANPC1RXRARXRB | |
| SCHEMBL27866376 | 0.71 | FEN1 (0.42) | FEN1SMN1; SMN2TSHRALOX5APRXRA | |
| SCHEMBL1759281 | 0.70 | TLR4 (0.42) | FEN1KDM4EALDH1A1PKMGRM5 | |
| SCHEMBL1759295 | 0.70 | FEN1 (0.42) | FEN1GRM5ALOX5APRXRARXRB | |
| SCHEMBL12772154 | 0.70 | FEN1 (0.45) | FEN1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1759014 | 0.70 | NFE2L2 (0.46) | KDM4EALDH1A1HPGDCYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493935-A2 | CATALYST COMPOUNDS AND USE THEREOF | Exxonmobil Chemical Patents Inc. (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011056431-A2 | CATALYST COMPOUNDS AND USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-05-12 | — | — | WO | disclosed |