SCHEMBL18979186

SCHEMBL18979186

O=C(O)CC/C=C/c1ccc(O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B10 O60218 3/20 0.52
AKR1B1 P15121 3/20 0.52
CA12 O43570 3/20 0.52
CA7 P43166 3/20 0.52
CA9 Q16790 3/20 0.52
CA14 Q9ULX7 3/20 0.52
TYR P14679 2/20 0.52
PKM P14618 2/20 0.52
CA4 P22748 2/20 0.52
CA6 P23280 2/20 0.52
CA5A P35218 2/20 0.52
CA5B Q9Y2D0 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
ESR1 P03372 1/20 0.52
CA3 P07451 1/20 0.52
DPP4 P27487 1/20 0.52
HCAR2 Q8TDS4 1/20 0.52
ESR2 Q92731 1/20 0.52
MAOB P27338 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9574442 1.00 AKR1B10 (0.52) AKR1B10AKR1B1CA12CA7CA9
SCHEMBL2642731 0.85 PAM (0.46) PAMRAB9AKMT2AALDH1A1MAPT
SCHEMBL2642729 0.85 PAM (0.46) PAMRAB9AKMT2AALDH1A1MAPT
SCHEMBL666894 0.84 PAM (0.64) HCAR2MAOBF3CYP2D6CYP2C9
SCHEMBL1231739 0.84 PAM (0.64) HCAR2MAOBF3CYP2D6CYP2C9
SCHEMBL1232837 0.84 PAM (0.64) HCAR2MAOBF3CYP2D6CYP2C9
SCHEMBL727447 0.83 HSD11B1 (0.50) HSD11B1PAMRAB9AKMT2AALDH1A1
SCHEMBL727448 0.83 HSD11B1 (0.50) HSD11B1PAMRAB9AKMT2AALDH1A1
SCHEMBL13870216 0.83 KMT2A (0.62) PAMCYP3A4RAB9AKMT2AALDH1A1
SCHEMBL2664660 0.83 PAM (0.44) PAMRAB9AKMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2952201-B1 Compositions of Alpinia galanga or Alpinia conchigera with high content of 1'S-1'-acetoxychavicol acetate suitable for pharmaceutical use NERTHUS APS (DK) 2017-06-21 EP claimed
CN-118773098-A Recombinant escherichia coli for synthesizing trans-anethole from head and construction method and application thereof 郑州大学 2024-10-15 CN disclosed
CN-118773101-A Recombinant escherichia coli for synthesizing trans-artemia from head and construction method and application 郑州大学 2024-10-15 CN disclosed
CN-118773099-A Recombinant escherichia coli for de novo synthesis of iso-preferably phenol, and construction method and application thereof 郑州大学 2024-10-15 CN disclosed
CN-118773097-A Recombinant escherichia coli for de novo synthesis of good-taste phenol, construction method and application 郑州大学 2024-10-15 CN disclosed
CN-118773100-A Recombinant escherichia coli for de novo synthesis of coumaroyl acetic acid as well as construction method and application thereof 郑州大学 2024-10-15 CN disclosed