SCHEMBL18979299

SCHEMBL18979299

CC(C)(C)Cc1ccc(CC(C)(C)C)c(N)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.43
GAA P10253 3/20 0.34
THRA P10827 1/20 0.34
THRB P10828 1/20 0.34
ALDH1A1 P00352 5/20 0.33
CYP3A4 P08684 3/20 0.33
TDP1 Q9NUW8 3/20 0.33
MAPT P10636 3/20 0.33
CYP1A2 P05177 3/20 0.33
ALOX15 P16050 3/20 0.33
HSD17B10 Q99714 3/20 0.33
KDM4E B2RXH2 2/20 0.33
POLB P06746 2/20 0.33
HPGD P15428 2/20 0.33
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
EGFR P00533 1/20 0.33
FYN P06241 1/20 0.33
APEX1 P27695 1/20 0.33
ADRA1A P35348 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9833902 0.83 CASP1 (0.44) ESR1GAAALDH1A1CYP3A4TDP1
SCHEMBL15156265 0.83 ESR1 (0.46) ESR1GAATHRATHRBALDH1A1
SCHEMBL23464032 0.81 ESR1 (0.45) ESR1GAATHRATHRBALDH1A1
SCHEMBL13153018 0.79 CASP1 (0.52) ESR1GAATHRATHRBALDH1A1
SCHEMBL21022055 0.78 ALDH1A1 (0.40) GAAALDH1A1SLC6A2SLC6A4SLC6A3
SCHEMBL20198782 0.78 ESR1 (0.52) ESR1GAATHRBALDH1A1CYP3A4
SCHEMBL26422443 0.78 ESR1 (0.42) ESR1GAATHRATHRBALDH1A1
SCHEMBL20609656 0.75 ESR1 (0.43) ESR1THRATHRBCYP3A4MAPT
SCHEMBL5376298 0.75 ESR1 (0.54) ESR1GAATHRATHRBALDH1A1
SCHEMBL23790349 0.75 ESR1 (0.43) ESR1THRATHRBRIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3674332-A1 ANTI-FOULING COATING Naval Group (FR) 2020-07-01 EP disclosed
EP-2599800-B1 COPOLYMER AND MANUFACTURING METHOD FOR SAME BRIDGESTONE CORP (JP) 2017-06-21 EP disclosed