Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | PNMT | P11086 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14565818 | 0.87 | SIGMAR1 (0.34) | ESR1FDPSGGPS1SLC6A2SLC6A4 | |
| SCHEMBL14565885 | 0.87 | ESR1 (0.37) | ESR1FDPSGGPS1SLC6A2SLC6A4 | |
| SCHEMBL16116520 | 0.86 | ESR1 (0.44) | ESR1FDPSGGPS1SLC6A2SLC6A4 | |
| SCHEMBL16116544 | 0.86 | ESR1 (0.39) | ESR1FDPSGGPS1SLC6A2SLC6A4 | |
| SCHEMBL74006 | 0.83 | IDO1 (0.52) | ESR1FDPSSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6886022 | 0.81 | GGPS1 (0.55) | ESR1GGPS1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9917301 | 0.79 | CYP3A4 (0.48) | ESR1FDPSSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL803376 | 0.79 | GGPS1 (0.37) | ESR1GGPS1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL15943539 | 0.79 | FDPS (0.34) | FDPSGGPS1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13873011 | 0.78 | IDO1 (0.50) | ESR1GGPS1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230043997-A1 | COMPOSITE MEMBRANE WITH NANOSELECTIVE SURFACE FOR ORGANIC SOLVENT NANOFILTRATION | W. L. GORE & ASSOCIATES, INC. | 2023-02-09 | — | — | US | disclosed |
| US-20220143002-A1 | SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF | SHANGHAITECH UNIVERSITY (CN) | 2022-05-12 | — | — | US | disclosed |
| WO-2020260393-A1 | MODIFICATION OF STRESS RESPONSE AND ADHESION BEHAVIOR OF DIELECTRIC THROUGH TUNING OF MECHANICAL PROPERTIES | FLEXENABLE LIMITED (GB) | 2020-12-30 | — | — | WO | disclosed |
| US-10167410-B2 | Using chemical vapor deposited films to control domain orientation in block copolymer thin films | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220143002-A1 | SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF | GLS, SQOR, GCDH | ESR1 3329/4885FDPS 602/4885GGPS1 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.