Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.30 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18980825 | 1.00 | KCNH2 (0.33) | KCNH2EGLN1IDO1KIF11MAOB | |
| SCHEMBL18980704 | 0.87 | RARB (0.36) | KCNH2EGLN1KIF11MAOBAOC3 | |
| SCHEMBL18980706 | 0.87 | RARB (0.36) | KCNH2EGLN1KIF11MAOBAOC3 | |
| SCHEMBL18980910 | 0.81 | KIF11 (0.35) | KCNH2EGLN1IDO1KIF11MAOB | |
| SCHEMBL1460921 | 0.80 | NPSR1 (0.45) | KCNH2 | |
| SCHEMBL1460918 | 0.80 | NPSR1 (0.45) | KCNH2 | |
| SCHEMBL18980593 | 0.79 | APP (0.41) | KCNH2EGLN1 | |
| SCHEMBL18980591 | 0.79 | APP (0.41) | KCNH2EGLN1 | |
| SCHEMBL3943848 | 0.72 | KIF11 (0.44) | KCNH2IDO1KIF11CHRNB2CHRNB4 | |
| SCHEMBL4020265 | 0.70 | GABRP (0.44) | KCNH2KIF11SLC6A4HRH3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10118169-B2 | Chiral ligand-based metal-organic frameworks for broad-scope asymmetric catalysis | THE UNIVERSITY OF CHICAGO (US) | 2018-11-06 | — | — | US | disclosed |
| US-20170173572-A1 | CHIRAL LIGAND-BASED METAL-ORGANIC FRAMEWORKS FOR BROAD-SCOPE ASYMMETRIC CATALYSIS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170173572-A1 | CHIRAL LIGAND-BASED METAL-ORGANIC FRAMEWORKS FOR BROAD-SCOPE ASYMMETRIC CATALYSIS | POF1B, FGFR1, COASY | KCNH2 1769/4885EGLN1 4418/4885IDO1 461/4885 |
| US-10118169-B2 | Chiral ligand-based metal-organic frameworks for broad-scope asymmetric catalysis | POF1B, FGFR1, COASY | KCNH2 1769/4885EGLN1 4418/4885IDO1 461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.