Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6654114 | 0.82 | ATM (0.52) | ATMCYP3A4GPR84MAPTMEN1 | |
| SCHEMBL9011712 | 0.78 | STING1 (0.49) | ATMCYP3A4GPR84MAPTMEN1 | |
| SCHEMBL28420595 | 0.78 | ATM (0.48) | ATMCYP3A4GPR84MAPTMEN1 | |
| SCHEMBL28346693 | 0.78 | STING1 (0.49) | ATMCYP3A4GPR84MAPTMEN1 | |
| SCHEMBL216179 | 0.78 | ATM (0.54) | ATMCYP3A4GPR84MAPTMEN1 | |
| Iodide SCHEMBL28673441 | 0.77 | ATM (0.47) | ATMCYP3A4GPR84MAPTMEN1 | |
| SCHEMBL4490274 | 0.76 | STING1 (0.59) | ATMGPR84ALDH1A1STING1GAA | |
| SCHEMBL22234314 | 0.76 | STING1 (0.48) | ATMGPR84MAPTALDH1A1STING1 | |
| SCHEMBL2864314 | 0.75 | MEN1 (0.52) | ATMCYP3A4GPR84MAPTMEN1 | |
| SCHEMBL28358937 | 0.75 | STING1 (0.46) | ATMCYP3A4GPR84MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115093361-A | Novel indole acylhydrazone compound and preparation method and application thereof | 华南师范大学 | 2022-09-23 | — | — | CN | claimed |
| CN-111349080-B | Indole acylhydrazone compound, preparation method thereof and application of indole acylhydrazone compound in prevention and treatment of plant diseases | 天津师范大学 | 2022-08-26 | — | — | CN | claimed |
| CN-110759913-B | Indolylhydrazone derivatives, preparation method thereof and application thereof in plant virus prevention and control, sterilization and disinsection | 南开大学 | 2022-01-28 | — | — | CN | claimed |
| CN-111349080-A | Indole acylhydrazone compound, preparation method thereof and application of indole acylhydrazone compound in prevention and treatment of plant diseases | 天津师范大学 | 2020-06-30 | — | — | CN | claimed |
| CN-110973144-A | Indole hydrazide-containing bactericidal composition | 京博农化科技有限公司 | 2020-04-10 | — | — | CN | claimed |
| CN-110759913-A | Indolylhydrazone derivatives, preparation method thereof and application thereof in plant virus prevention and control, sterilization and disinsection | 南开大学 | 2020-02-07 | — | — | CN | claimed |
| EP-1649857-A2 | New use of glutamate antagonists for the treatment of cancer | Ikonomidou, Hrissanthi (DE) | 2006-04-26 | — | — | EP | claimed |
| US-20050054650-A1 | Use of glutamate antagonists for the treatment of cancer | IKONOMIDOU HRISSANTHI (DE) | 2005-03-10 | — | — | US | claimed |
| EP-1124553-A1 | NEW USE OF GLUTAMATE ANTAGONISTS FOR THE TREATMENT OF CANCER | Ikonomidou, Hrissanthi (DE) | 2001-08-22 | — | — | EP | claimed |
| EP-1002535-A1 | New use of glutamate antagonists for the treatment of cancer | Ikonomidou, Hrissanthi (DE) | 2000-05-24 | — | — | EP | claimed |
| WO-2000024395-A1 | NEW USE OF GLUTAMATE ANTAGONISTS FOR THE TREATMENT OF CANCER | IKONOMIDOU HRISSANTHI (DE) | 2000-05-04 | — | — | WO | claimed |
| CN-115772513-A | D-carbamyl hydrolase mutant, gene, expression vector and application thereof | 江南大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-115093361-A | Novel indole acylhydrazone compound and preparation method and application thereof | 华南师范大学 | 2022-09-23 | — | — | CN | disclosed |
| CN-111349038-B | Indolylhydrazone compounds, preparation method thereof and application thereof in preventing and treating plant diseases | 天津师范大学 | 2022-09-16 | — | — | CN | disclosed |
| CN-111349038-B | Indolylhydrazone compounds, preparation method thereof and application thereof in preventing and treating plant diseases | 天津师范大学 | 2022-09-16 | — | — | CN | disclosed |
| WO-2003015713-A2 | TREATMENT OF GLIAL TUMORS WITH GLUTAMATE ANTAGONISTS | NEDERGAARD MAIKEN (US) | 2003-02-27 | — | — | WO | disclosed |
| EP-1124553-A1 | NEW USE OF GLUTAMATE ANTAGONISTS FOR THE TREATMENT OF CANCER | Ikonomidou, Hrissanthi (DE) | 2001-08-22 | — | — | EP | disclosed |
| EP-1002535-A1 | New use of glutamate antagonists for the treatment of cancer | Ikonomidou, Hrissanthi (DE) | 2000-05-24 | — | — | EP | disclosed |
| WO-2000024395-A1 | NEW USE OF GLUTAMATE ANTAGONISTS FOR THE TREATMENT OF CANCER | IKONOMIDOU HRISSANTHI (DE) | 2000-05-04 | — | — | WO | disclosed |
| US-4476137-A | ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1984-10-09 | — | — | US | disclosed |