Iodide

Iodide

SCHEMBL28673441

I.INc1c[nH]c2ccccc12

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.47
GPR84 Q9NQS5 2/20 0.45
MEN1 O00255 1/20 0.45
CYP3A4 P08684 1/20 0.45
MAPT P10636 1/20 0.45
AHR P35869 1/20 0.45
KMT2A Q03164 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
STING1 Q86WV6 7/20 0.44
IMPDH2 P12268 2/20 0.42
IMPDH1 P20839 1/20 0.42
CYP2A6 P11509 1/20 0.42
HTR2A P28223 3/20 0.42
HTR2C P28335 3/20 0.42
HTR2B P41595 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6654114 0.80 ATM (0.52) ATMGPR84MEN1CYP3A4MAPT
SCHEMBL28346693 0.77 STING1 (0.49) ATMGPR84MEN1CYP3A4MAPT
SCHEMBL216179 0.77 ATM (0.54) ATMGPR84MEN1CYP3A4MAPT
SCHEMBL1898356 0.77 ATM (0.48) ATMGPR84MEN1CYP3A4MAPT
SCHEMBL28420595 0.77 ATM (0.48) ATMGPR84MEN1CYP3A4MAPT
SCHEMBL9011712 0.77 STING1 (0.49) ATMGPR84MEN1CYP3A4MAPT
SCHEMBL2864314 0.73 MEN1 (0.52) ATMGPR84MEN1CYP3A4MAPT
SCHEMBL5512885 0.73 STING1 (0.46) ATMGPR84MEN1CYP3A4MAPT
SCHEMBL28358937 0.73 STING1 (0.46) ATMGPR84MEN1CYP3A4MAPT
SCHEMBL17595410 0.73 IMPDH2 (0.55) ATMGPR84MEN1CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113964273-B Compound, perovskite thin-film solar cell and preparation method thereof 义乌协同创新研究院 2023-04-07 CN disclosed
CN-113964273-A Compound, perovskite thin-film solar cell and preparation method thereof 义乌协同创新研究院 2022-01-21 CN disclosed