Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | STING1 | Q86WV6 | 7/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL4500293 | 0.89 | STING1 (0.52) | ATMMEN1KMT2AGPR84MAPT | |
| SCHEMBL6654114 | 0.82 | ATM (0.52) | ATMMEN1KMT2AGPR84MAPT | |
| SCHEMBL28420595 | 0.78 | ATM (0.48) | ATMMEN1KMT2AGPR84MAPT | |
| SCHEMBL28346693 | 0.78 | STING1 (0.49) | ATMMEN1KMT2AGPR84MAPT | |
| SCHEMBL1898356 | 0.78 | ATM (0.48) | ATMMEN1KMT2AGPR84MAPT | |
| SCHEMBL9011712 | 0.78 | STING1 (0.49) | ATMMEN1KMT2AGPR84MAPT | |
| SCHEMBL22328234 | 0.78 | ATM (0.48) | ATMMEN1KMT2AGPR84MAPT | |
| SCHEMBL30753171 | 0.78 | HTR2A (0.51) | ATMMEN1KMT2AGPR84MAPT | |
| SCHEMBL1260955 | 0.78 | HTR2A (0.51) | ATMMEN1KMT2AGPR84MAPT | |
| SCHEMBL25571556 | 0.78 | GPR84 (0.50) | ATMMEN1KMT2AGPR84MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118908874-A | PAD4 inhibitor, preparation method thereof and application thereof in preparation of anti-pulmonary fibrosis drugs | 首都医科大学 | 2024-11-08 | — | — | CN | claimed |
| CN-116133442-A | Perovskite solar cell based on organic molecule modified lithium salt doped hole transport layer | 陕西师范大学 | 2023-05-16 | — | — | CN | claimed |
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| CN-108892634-A | A kind of indole methyl amino benzenes compounds and its application | 浙江工业大学 | 2018-11-27 | — | — | CN | claimed |
| CN-104530013-B | Pyrazol acid amide compounds based on indole ring as disinfectant use in agriculture purposes | 中国农业大学 | 2016-06-29 | — | — | CN | claimed |
| CN-104530013-A | Application of indole ring-based pyrazole amide compound used as agricultural fungicide | UNIV CHINA AGRICULTURAL | 2015-04-22 | — | — | CN | claimed |
| CN-103261156-A | New compounds for the treatment of neurodegenerative diseases | LEUVEN K U RES & DEV | 2013-08-21 | — | — | CN | claimed |
| US-20090028796-A1 | PESTICIDAL COMPOSITION COMPRISING INDOLE DERIVATES | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e. V. (DE) | 2009-01-29 | — | — | US | claimed |
| EP-1978805-A1 | PESTICIDAL COMPOSITION COMPRISING INDOLE DERIVATES | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2008-10-15 | — | — | EP | claimed |
| WO-2007085660-A1 | PESTICIDAL COMPOSITION COMPRISING INDOLE DERIVATES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2007-08-02 | — | — | WO | claimed |
| EP-0552489-B1 | Peptide, production and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-03-04 | — | — | EP | claimed |
| US-5614497-A | TREATMENT OF HYPERTENSION, CARDIOVASCULAR DISEASE AND RENAL DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-03-25 | — | — | US | claimed |
| EP-0552489-A2 | Peptide, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-07-28 | — | — | EP | claimed |
| EP-0037271-B1 | INDOLE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | TORAY INDUSTRIES, INC. (JP) | 1984-01-18 | — | — | EP | claimed |
| JP-53009763-A | — | — | None | — | — | JP | disclosed |
| CN-116133442-B | Perovskite solar cell based on organic molecule modified lithium salt doped hole transport layer | SHAANXI NORMAL UNIVERSITY (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-118908874-A | PAD4 inhibitor, preparation method thereof and application thereof in preparation of anti-pulmonary fibrosis drugs | 首都医科大学 | 2024-11-08 | — | — | CN | disclosed |
| WO-2000042213-A1 | A NOVEL METHOD FOR DESIGNING PROTEIN KINASE INHIBITORS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2000-07-20 | — | — | WO | disclosed |
| CN-1109780-A | Sustained-release preparation of anti-endothelin substance | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-10-11 | — | — | CN | disclosed |
| JP-S539763-A | METHYLIDENE-AMINE DERIVATIVES | HODOGAYA CHEM CO LTD | 1978-01-28 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090028796-A1 | PESTICIDAL COMPOSITION COMPRISING INDOLE DERIVATES | IDO1, IDO2, INMT | ATM 4657/4885MEN1 3306/4885KMT2A 3257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.