SCHEMBL1898522

SCHEMBL1898522

Cc1ccc([S+]([O-])Cl)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 7/20 0.44
TDP1 Q9NUW8 1/20 0.44
GAA P10253 2/20 0.36
ALDH1A1 P00352 3/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA7 P43166 2/20 0.35
CA9 Q16790 2/20 0.35
HSD17B10 Q99714 1/20 0.33
CA12 O43570 1/20 0.33
CA3 P07451 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
TLR9 Q9NR96 1/20 0.32
TSHR P16473 3/20 0.32
LMNA P02545 2/20 0.32
ALOX12 P18054 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
IDO1 P14902 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9022447 0.85
SCHEMBL4401131 0.77 ACHE (0.50) ACHETDP1GAAALDH1A1CA1
SCHEMBL563967 0.77 ACHE (0.50) ACHETDP1GAAALDH1A1CA1
SCHEMBL235851 0.77 ACHE (0.50) ACHETDP1GAAALDH1A1CA1
SCHEMBL254471 0.74 ACHE (0.47) ACHETDP1GAAALDH1A1CA1
SCHEMBL1094237 0.74 ACHE (0.47) ACHETDP1GAAALDH1A1CA1
SCHEMBL280535 0.74 ACHE (0.47) ACHETDP1GAAALDH1A1CA1
SCHEMBL14231073 0.74 ACHE (0.47) ACHETDP1GAAALDH1A1CA1
SCHEMBL5520567 0.74 LMNA (0.47) TDP1ALDH1A1CA1CA2CA7
SCHEMBL13823044 0.72 CA1 (0.35) ACHECA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117865859-A Preparation method of enantiomerically pure p-toluenesulfonamide 常州琦诺生物科技有限公司 2024-04-12 CN claimed
CN-108558714-B Preparation method of chiral optical pure p-toluenesulfinamide 上海李氏化学科技有限公司 2020-10-16 CN claimed
US-4530795-A Process for preparation of 16 α-methyl corticoids from Δ16 -steroids THE UPJOHN COMPANY (US) 1985-07-23 US claimed
US-4102907-A Desulfinylation process for preparing androsta-4,9(11)-diene-3,17-dione THE UPJOHN COMPANY (US) 1978-07-25 US claimed
EP-4741427-A1 GLYCAN, PREPARATION METHOD THEREFOR AND USE THEREOF, AND ANTI-TUMOR DRUG Peking University (CN) 2026-05-13 EP disclosed
EP-3634951-B1 NOVEL SUBSTITUTED SULFOXIMINE COMPOUNDS ZYDUS LIFESCIENCES LTD (IN) 2024-07-10 EP disclosed
EP-3634951-B1 NOVEL SUBSTITUTED SULFOXIMINE COMPOUNDS ZYDUS LIFESCIENCES LTD (IN) 2024-07-10 EP disclosed
CN-117865859-A Preparation method of enantiomerically pure p-toluenesulfonamide 常州琦诺生物科技有限公司 2024-04-12 CN disclosed
WO-2024006742-A2 NRF2 PROTEIN DEGRADERS DRACEN PHARMACEUTICALS, INC. (US) 2024-01-04 WO disclosed
WO-2023240156-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES, AND METHODS OF SYNTHESIS AND USE THEREOF TIDAL THERAPEUTICS, INC. (US) 2023-12-14 WO disclosed
CN-117088865-A 3CLpro protease inhibitor related substance and preparation method thereof 齐鲁制药有限公司 2023-11-21 CN disclosed
EP-3814331-B9 NOVEL LXR MODULATORS WITH BICYCLIC CORE MOIETY ORSOBIO INC (US) 2023-08-09 EP disclosed
US-4605714-A TRANSITION METAL- TALC- ORGANOALUMINUM COMPOUND-CONTAINING COORDINATION CATALYST IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) 1986-08-12 US disclosed
US-4554361-A Process for the preparation of a bicyclic lactone through a sulfonated derivative ROUSSEL UCLAF (FR) 1985-11-19 US disclosed
US-4548916-A OLEFIN POLYMERIZATION CATALYST CONTAINING MIXTURE OF TRANSITION METAL WITH TALC OR AROMATIC CARBOXYLIC ACID SALT IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) 1985-10-22 US disclosed
EP-0118172-A1 Catalyst, production and use IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-09-12 EP disclosed
US-4331605-A Lactone ring containing sulfonic acid esters ROUSSEL UCLAF (FR) 1982-05-25 US disclosed
US-4267174-A AND PROCESS FOR ADMINISTERING BOEHRINGER MANNHEIM, GMBH (DE) 1981-05-12 US disclosed
US-4102907-A Desulfinylation process for preparing androsta-4,9(11)-diene-3,17-dione THE UPJOHN COMPANY (US) 1978-07-25 US disclosed
US-3943154-A PLANT AND ANIMAL GROWTH REGULATORS SANITIZED INCORPORATED (US) 1976-03-09 US disclosed